Interaction of indoleamine-2,3-dioxyagnase and CD4+ CD25+ regulatory T cells in tumor immune escape

Hui Wang, Ke Pan, Jian Chuan Xia

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

There are numerous factors involved in the tumor evasion from immune surveillance. Recently, considerable attention has been given to indoleamine 2,3-dioxygenase (IDO) and CD4+CD25+ regulatory T cells (Tregs). The interaction between the two may play a crucial role in tumor immune escape. This article reviews the correlation between IDO and Tregs in immune escape of tumors.

Original languageEnglish (US)
Pages (from-to)184-187
Number of pages4
JournalChinese Journal of Cancer
Volume28
Issue number2
StatePublished - 2009

Keywords

  • CD4+CD25+ regulatory T cells
  • Immune escape
  • Indoleamine-2,3-dioxygenase
  • Tumor

ASJC Scopus subject areas

  • Oncology

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