Intrathecal treatments for leptomeningeal metastases

LMM represents many challenges in both the diagnosis and treatment. The prognosis of patients with LMM remains poor with survival measured in weeks to months despite aggressive management. Managing the patients with LMM requires the development of rapid and improved tools for fast diagnosis and early, non-delayed intervention. However, an extensive field for both diagnosis and treatment remains open for exploration. Future directions may include determining the appropriate treatment for specific patient populations, using personalized medicine when appropriate and feasible, optimal route of administration of drug delivery into the CSF, and aggressive prompt treatment interventions.