TY - JOUR
T1 - Invasive Breast Carcinoma Tumor Size on Core Needle Biopsy
T2 - Analysis of Practice Patterns and Effect on Final Pathologic Tumor Stage
AU - Agosto-Arroyo, Emmanuel
AU - Tahmasbi, Maryam
AU - Al Diffalha, Sameer
AU - Khazai, Laila
AU - Xiong, Yin
AU - Rosa, Marilin
N1 - Publisher Copyright:
© 2018 Elsevier Inc.
PY - 2018/10
Y1 - 2018/10
N2 - In this study we evaluated the effect of core needle biopsy (CNB) tumor size on final pathologic tumor (pT) stage. The laboratory information system was retrospectively reviewed for breast excisional specimens. In 82 of 870 cases (9.4%) the CNB contains the most accurate tumor size for pT staging. Including the largest linear tumor extent on the CNB report is recommended. Introduction: In the absence of nodal metastasis, pathologic tumor (pT) size remains one of the most important factors in adjuvant treatment decisions and patient prognosis in breast cancer. The aim of this study was to evaluate the effect of core needle biopsy (CNB) tumor size on final pT stage. Materials and Methods: Our information system was searched to identify all patients who underwent excisional procedures for invasive breast carcinoma from January 1 2014 to December 31, 2015. The tumor size on CNB and final excision, the number of cases in which the CNB size was larger, and the percentage of cases in which using the CNB tumor size changed the final pT stage were recorded. Results: From 1380 primary breast excisions/mastectomies, a total of 870 cases were included. In 82 (9.4%) the CNB tumor size was larger (63 of 82 cases) or no residual tumor was identified on excision (19 of 82 cases). From these 82 cases, 40 (48.7%) were properly staged on the basis of CNB tumor size, 16 (19.5%) were not staged, and 26 (31.7%) were staged using the final excision tumor size. Change in stage occurred in 7 of these 26 patients. Conclusion: Our study revealed that in most cases, the largest tumor size is found in the excision/mastectomy specimen. However, in 9.4% (82 of 870), the CNB contains the most accurate tumor size for pT staging. On the basis of our results, including the largest linear tumor extent on the CNB report is recommended.
AB - In this study we evaluated the effect of core needle biopsy (CNB) tumor size on final pathologic tumor (pT) stage. The laboratory information system was retrospectively reviewed for breast excisional specimens. In 82 of 870 cases (9.4%) the CNB contains the most accurate tumor size for pT staging. Including the largest linear tumor extent on the CNB report is recommended. Introduction: In the absence of nodal metastasis, pathologic tumor (pT) size remains one of the most important factors in adjuvant treatment decisions and patient prognosis in breast cancer. The aim of this study was to evaluate the effect of core needle biopsy (CNB) tumor size on final pT stage. Materials and Methods: Our information system was searched to identify all patients who underwent excisional procedures for invasive breast carcinoma from January 1 2014 to December 31, 2015. The tumor size on CNB and final excision, the number of cases in which the CNB size was larger, and the percentage of cases in which using the CNB tumor size changed the final pT stage were recorded. Results: From 1380 primary breast excisions/mastectomies, a total of 870 cases were included. In 82 (9.4%) the CNB tumor size was larger (63 of 82 cases) or no residual tumor was identified on excision (19 of 82 cases). From these 82 cases, 40 (48.7%) were properly staged on the basis of CNB tumor size, 16 (19.5%) were not staged, and 26 (31.7%) were staged using the final excision tumor size. Change in stage occurred in 7 of these 26 patients. Conclusion: Our study revealed that in most cases, the largest tumor size is found in the excision/mastectomy specimen. However, in 9.4% (82 of 870), the CNB contains the most accurate tumor size for pT staging. On the basis of our results, including the largest linear tumor extent on the CNB report is recommended.
KW - Core biopsy
KW - Core needle
KW - Invasive breast cancer
KW - Stage
KW - Tumor size
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U2 - 10.1016/j.clbc.2018.02.013
DO - 10.1016/j.clbc.2018.02.013
M3 - Article
C2 - 29622383
AN - SCOPUS:85044763793
SN - 1526-8209
VL - 18
SP - e1027-e1030
JO - Clinical breast cancer
JF - Clinical breast cancer
IS - 5
ER -