Invasive Carcinoma With Skin Adnexal Trichilemmal Hair Follicular Differentiation Occurring in the Breast: A Case Report With Detailed Immunohistochemical and Molecular Analysis

Oluwaseyi Olayinka; Solange E. Cox; Azadeh Nasrazadani; Erika Resetkova; Doina Ivan; Lavinia P. Middleton

doi:10.1177/10668969231189166

Invasive Carcinoma With Skin Adnexal Trichilemmal Hair Follicular Differentiation Occurring in the Breast: A Case Report With Detailed Immunohistochemical and Molecular Analysis

Oluwaseyi Olayinka, Solange E. Cox, Azadeh Nasrazadani, Erika Resetkova, Doina Ivan, Lavinia P. Middleton

Research output: Contribution to journal › Article › peer-review

Abstract

Cutaneous-type adnexal tumors involving the breast are rare and create a diagnostic dilemma as they are often indistinguishable from primary mammary neoplasms. Tumors showing hair follicular differentiation are particularly challenging due to their rarity and the subtle appreciation of the intricate microanatomy of the hair follicle. We report a triple negative cutaneous-type adnexal carcinoma with follicular differentiation involving the breast to bring attention to the existence of these specialized group of tumors which should be managed differently from conventional triple negative carcinomas of the breast.

Original language	English (US)
Journal	International Journal of Surgical Pathology
DOIs	https://doi.org/10.1177/10668969231189166
State	Accepted/In press - 2023

Keywords

adnexal tumors
breast
cutaneous
follicular differentiation

ASJC Scopus subject areas

Surgery
Anatomy
Pathology and Forensic Medicine

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10.1177/10668969231189166

Cite this

Olayinka, O., Cox, S. E., Nasrazadani, A., Resetkova, E., Ivan, D., & Middleton, L. P. (Accepted/In press). Invasive Carcinoma With Skin Adnexal Trichilemmal Hair Follicular Differentiation Occurring in the Breast: A Case Report With Detailed Immunohistochemical and Molecular Analysis. International Journal of Surgical Pathology. https://doi.org/10.1177/10668969231189166

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abstract = "Cutaneous-type adnexal tumors involving the breast are rare and create a diagnostic dilemma as they are often indistinguishable from primary mammary neoplasms. Tumors showing hair follicular differentiation are particularly challenging due to their rarity and the subtle appreciation of the intricate microanatomy of the hair follicle. We report a triple negative cutaneous-type adnexal carcinoma with follicular differentiation involving the breast to bring attention to the existence of these specialized group of tumors which should be managed differently from conventional triple negative carcinomas of the breast.",

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AU - Ivan, Doina

AU - Middleton, Lavinia P.

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N2 - Cutaneous-type adnexal tumors involving the breast are rare and create a diagnostic dilemma as they are often indistinguishable from primary mammary neoplasms. Tumors showing hair follicular differentiation are particularly challenging due to their rarity and the subtle appreciation of the intricate microanatomy of the hair follicle. We report a triple negative cutaneous-type adnexal carcinoma with follicular differentiation involving the breast to bring attention to the existence of these specialized group of tumors which should be managed differently from conventional triple negative carcinomas of the breast.

AB - Cutaneous-type adnexal tumors involving the breast are rare and create a diagnostic dilemma as they are often indistinguishable from primary mammary neoplasms. Tumors showing hair follicular differentiation are particularly challenging due to their rarity and the subtle appreciation of the intricate microanatomy of the hair follicle. We report a triple negative cutaneous-type adnexal carcinoma with follicular differentiation involving the breast to bring attention to the existence of these specialized group of tumors which should be managed differently from conventional triple negative carcinomas of the breast.

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KW - cutaneous

KW - follicular differentiation

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Invasive Carcinoma With Skin Adnexal Trichilemmal Hair Follicular Differentiation Occurring in the Breast: A Case Report With Detailed Immunohistochemical and Molecular Analysis

Abstract

Keywords

ASJC Scopus subject areas

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