TY - JOUR
T1 - Invasive Thymoma with Right Upper Lobe Endobronchial Lesion and Autoimmune Enteropathy
AU - Datar, Saumil
AU - De La Garza, Henriette
AU - Srinivasan, Aditya
AU - Iliescu, Gloria
AU - Kalhor, Neda
AU - Grosu, Horiana
N1 - Publisher Copyright:
© 2020 Saumil Datar et al.
PY - 2020
Y1 - 2020
N2 - Thymomas are slow-growing neoplasia arising from the epithelial cells of the thymus that usually present with respiratory symptoms, superior vena cava syndrome, or parathymic syndromes. Approximately 30% of thymomas develop myasthenia gravis. An additional 5% of patients with thymomas have other systemic syndromes, including rheumatoid arthritis, thyroiditis, red cell aplasia, systemic lupus erythematosus, and Cushing syndrome. Rarely, patients can present with diarrhea due to thymoma-associated autoimmune gastrointestinal pathologies that include Good syndrome (acquired hypogammaglobulinemia), thymoma- associated multiorgan autoimmunity, and autoimmune enteropathy. We present an uncommon and interesting case of an invasive metastatic thymoma with right upper lobe endobronchial lesion and autoimmune enteropathy in a 27-year-old female. The novelty of this case lay in the findings of extensive metastatic thymoma with right upper lobe endobronchial disease and autoimmune diarrhea.
AB - Thymomas are slow-growing neoplasia arising from the epithelial cells of the thymus that usually present with respiratory symptoms, superior vena cava syndrome, or parathymic syndromes. Approximately 30% of thymomas develop myasthenia gravis. An additional 5% of patients with thymomas have other systemic syndromes, including rheumatoid arthritis, thyroiditis, red cell aplasia, systemic lupus erythematosus, and Cushing syndrome. Rarely, patients can present with diarrhea due to thymoma-associated autoimmune gastrointestinal pathologies that include Good syndrome (acquired hypogammaglobulinemia), thymoma- associated multiorgan autoimmunity, and autoimmune enteropathy. We present an uncommon and interesting case of an invasive metastatic thymoma with right upper lobe endobronchial lesion and autoimmune enteropathy in a 27-year-old female. The novelty of this case lay in the findings of extensive metastatic thymoma with right upper lobe endobronchial disease and autoimmune diarrhea.
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U2 - 10.1155/2020/6396915
DO - 10.1155/2020/6396915
M3 - Article
C2 - 32637181
AN - SCOPUS:85111573270
SN - 2090-6846
VL - 2020
JO - Case Reports in Pulmonology
JF - Case Reports in Pulmonology
M1 - 6396915
ER -