Investigation of organ dose variation with adult head size and pediatric age for neuro-interventional projections

Zhenyu Xiong; Sarath Vijayan; Chao Guo; Stephen Rudin; Daniel R. Bednarek

doi:10.1117/12.2293958

Investigation of organ dose variation with adult head size and pediatric age for neuro-interventional projections

Zhenyu Xiong, Sarath Vijayan, Chao Guo, Stephen Rudin, Daniel R. Bednarek

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Scopus citations

Abstract

The purpose of this study was to evaluate the effect of patient head size on radiation dose to radiosensitive organs, such as the eye lens, brain and spinal cord in fluoroscopically guided neuro-interventional procedures and CBCT scans of the head. The Toshiba Infinix C-Arm System was modeled in BEAMnrc/EGSnrc Monte-Carlo code and patient organ and effective doses were calculated in DOSxynrc/EGSnrc for CBCT and interventional procedures. X-ray projections from different angles, CBCT scans, and neuro-interventional procedures were simulated on a computational head phantom for the range of head sizes in the adult population and for different pediatric ages. The difference of left-eye lens dose between the mean head size and the mean ± 1 standard deviation (SD) ranges from 20% to 300% for projection angles of 0° to 90° RAO. The differences for other organs do not vary as much and is only about 10% for the brain. For a LCI-High CBCT protocol, the difference between mean and mean ± 1 SD head size is about 100% for lens dose and only 10% for mean and peak brain dose; the difference between 20 and 3 year-old mean head size is an increase of about 200% for the eye lens dose and only 30% for mean and peak brain dose. Dose for all organs increases with decreasing head size for the same reference point air kerma. These results will allow size-specific dose estimates to be made using software such as our dose tracking system (DTS).

Original language	English (US)
Title of host publication	Medical Imaging 2018
Subtitle of host publication	Physics of Medical Imaging
Editors	Taly Gilat Schmidt, Guang-Hong Chen, Joseph Y. Lo
Publisher	SPIE
ISBN (Electronic)	9781510616356
DOIs	https://doi.org/10.1117/12.2293958
State	Published - 2018
Externally published	Yes
Event	Medical Imaging 2018: Physics of Medical Imaging - Houston, United States Duration: Feb 12 2018 → Feb 15 2018

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10573
ISSN (Print)	1605-7422

Other

Other	Medical Imaging 2018: Physics of Medical Imaging
Country/Territory	United States
City	Houston
Period	2/12/18 → 2/15/18

Keywords

CBCT
EGSnrc
head size
Monte Carlo
organ dose
X-ray projection

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Biomaterials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging

Access to Document

10.1117/12.2293958

Cite this

Xiong, Z., Vijayan, S., Guo, C., Rudin, S., & Bednarek, D. R. (2018). Investigation of organ dose variation with adult head size and pediatric age for neuro-interventional projections. In T. G. Schmidt, G.-H. Chen, & J. Y. Lo (Eds.), Medical Imaging 2018: Physics of Medical Imaging Article 105734D (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10573). SPIE. https://doi.org/10.1117/12.2293958

Investigation of organ dose variation with adult head size and pediatric age for neuro-interventional projections. / Xiong, Zhenyu; Vijayan, Sarath; Guo, Chao et al.
Medical Imaging 2018: Physics of Medical Imaging. ed. / Taly Gilat Schmidt; Guang-Hong Chen; Joseph Y. Lo. SPIE, 2018. 105734D (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10573).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Xiong, Z, Vijayan, S, Guo, C, Rudin, S & Bednarek, DR 2018, Investigation of organ dose variation with adult head size and pediatric age for neuro-interventional projections. in TG Schmidt, G-H Chen & JY Lo (eds), Medical Imaging 2018: Physics of Medical Imaging., 105734D, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10573, SPIE, Medical Imaging 2018: Physics of Medical Imaging, Houston, United States, 2/12/18. https://doi.org/10.1117/12.2293958

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title = "Investigation of organ dose variation with adult head size and pediatric age for neuro-interventional projections",

abstract = "The purpose of this study was to evaluate the effect of patient head size on radiation dose to radiosensitive organs, such as the eye lens, brain and spinal cord in fluoroscopically guided neuro-interventional procedures and CBCT scans of the head. The Toshiba Infinix C-Arm System was modeled in BEAMnrc/EGSnrc Monte-Carlo code and patient organ and effective doses were calculated in DOSxynrc/EGSnrc for CBCT and interventional procedures. X-ray projections from different angles, CBCT scans, and neuro-interventional procedures were simulated on a computational head phantom for the range of head sizes in the adult population and for different pediatric ages. The difference of left-eye lens dose between the mean head size and the mean ± 1 standard deviation (SD) ranges from 20% to 300% for projection angles of 0° to 90° RAO. The differences for other organs do not vary as much and is only about 10% for the brain. For a LCI-High CBCT protocol, the difference between mean and mean ± 1 SD head size is about 100% for lens dose and only 10% for mean and peak brain dose; the difference between 20 and 3 year-old mean head size is an increase of about 200% for the eye lens dose and only 30% for mean and peak brain dose. Dose for all organs increases with decreasing head size for the same reference point air kerma. These results will allow size-specific dose estimates to be made using software such as our dose tracking system (DTS).",

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AB - The purpose of this study was to evaluate the effect of patient head size on radiation dose to radiosensitive organs, such as the eye lens, brain and spinal cord in fluoroscopically guided neuro-interventional procedures and CBCT scans of the head. The Toshiba Infinix C-Arm System was modeled in BEAMnrc/EGSnrc Monte-Carlo code and patient organ and effective doses were calculated in DOSxynrc/EGSnrc for CBCT and interventional procedures. X-ray projections from different angles, CBCT scans, and neuro-interventional procedures were simulated on a computational head phantom for the range of head sizes in the adult population and for different pediatric ages. The difference of left-eye lens dose between the mean head size and the mean ± 1 standard deviation (SD) ranges from 20% to 300% for projection angles of 0° to 90° RAO. The differences for other organs do not vary as much and is only about 10% for the brain. For a LCI-High CBCT protocol, the difference between mean and mean ± 1 SD head size is about 100% for lens dose and only 10% for mean and peak brain dose; the difference between 20 and 3 year-old mean head size is an increase of about 200% for the eye lens dose and only 30% for mean and peak brain dose. Dose for all organs increases with decreasing head size for the same reference point air kerma. These results will allow size-specific dose estimates to be made using software such as our dose tracking system (DTS).

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Investigation of organ dose variation with adult head size and pediatric age for neuro-interventional projections

Abstract

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Keywords

ASJC Scopus subject areas

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