Iron-containing pathologies of the spleen: magnetic resonance imaging features with pathologic correlation

Nikita Consul; Sidra Javed-Tayyab; Ajaykumar C. Morani; Christine O. Menias; Meghan G. Lubner; Khaled M. Elsayes

doi:10.1007/s00261-020-02709-x

Iron-containing pathologies of the spleen: magnetic resonance imaging features with pathologic correlation

Nikita Consul, Sidra Javed-Tayyab, Ajaykumar C. Morani, Christine O. Menias, Meghan G. Lubner, Khaled M. Elsayes

Abdominal Imaging

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

Systemic and non-systemic pathologies that involve iron deposition within the spleen have characteristic features on MRI due to the susceptibility properties of deposited iron, or hemosiderin. These lesions will have signal loss on longer echo sequences due to the T2* effect when evaluated with dual-echo gradient-echo sequences. The pathophysiology of systemic and localized iron sequestration disease processes can elucidate an underlying diagnosis based on these imaging features in conjunction with clinical information.

Original language	English (US)
Pages (from-to)	1016-1026
Number of pages	11
Journal	Abdominal Radiology
Volume	46
Issue number	3
DOIs	https://doi.org/10.1007/s00261-020-02709-x
State	Published - Mar 2021

Keywords

Hemosiderin
Iron deposition
MRI
Spleen
Superparamagnetic
T2* effect

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging
Gastroenterology
Urology

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10.1007/s00261-020-02709-x

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title = "Iron-containing pathologies of the spleen: magnetic resonance imaging features with pathologic correlation",

abstract = "Systemic and non-systemic pathologies that involve iron deposition within the spleen have characteristic features on MRI due to the susceptibility properties of deposited iron, or hemosiderin. These lesions will have signal loss on longer echo sequences due to the T2* effect when evaluated with dual-echo gradient-echo sequences. The pathophysiology of systemic and localized iron sequestration disease processes can elucidate an underlying diagnosis based on these imaging features in conjunction with clinical information.",

keywords = "Hemosiderin, Iron deposition, MRI, Spleen, Superparamagnetic, T2* effect",

author = "Nikita Consul and Sidra Javed-Tayyab and Morani, {Ajaykumar C.} and Menias, {Christine O.} and Lubner, {Meghan G.} and Elsayes, {Khaled M.}",

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year = "2021",

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language = "English (US)",

volume = "46",

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TY - JOUR

T1 - Iron-containing pathologies of the spleen

T2 - magnetic resonance imaging features with pathologic correlation

AU - Consul, Nikita

AU - Javed-Tayyab, Sidra

AU - Morani, Ajaykumar C.

AU - Menias, Christine O.

AU - Lubner, Meghan G.

AU - Elsayes, Khaled M.

PY - 2021/3

Y1 - 2021/3

N2 - Systemic and non-systemic pathologies that involve iron deposition within the spleen have characteristic features on MRI due to the susceptibility properties of deposited iron, or hemosiderin. These lesions will have signal loss on longer echo sequences due to the T2* effect when evaluated with dual-echo gradient-echo sequences. The pathophysiology of systemic and localized iron sequestration disease processes can elucidate an underlying diagnosis based on these imaging features in conjunction with clinical information.

AB - Systemic and non-systemic pathologies that involve iron deposition within the spleen have characteristic features on MRI due to the susceptibility properties of deposited iron, or hemosiderin. These lesions will have signal loss on longer echo sequences due to the T2* effect when evaluated with dual-echo gradient-echo sequences. The pathophysiology of systemic and localized iron sequestration disease processes can elucidate an underlying diagnosis based on these imaging features in conjunction with clinical information.

KW - Hemosiderin

KW - Iron deposition

KW - MRI

KW - Spleen

KW - Superparamagnetic

KW - T2 effect

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AN - SCOPUS:85091615248

SN - 2366-004X

VL - 46

SP - 1016

EP - 1026

JO - Abdominal Radiology

JF - Abdominal Radiology

IS - 3

ER -

Iron-containing pathologies of the spleen: magnetic resonance imaging features with pathologic correlation

Abstract

Keywords

ASJC Scopus subject areas

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