TY - JOUR
T1 - Islet cell tumors metastatic to the liver
T2 - Effective palliation by sequential hepatic artery embolization
AU - Ajani, J. A.
AU - Carrasco, C. H.
AU - Charnsangavej, C.
AU - Samaan, N. A.
AU - Levin, B.
AU - Wallace, S.
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 1988
Y1 - 1988
N2 - The value of sequential percutaneous hepatic artery embolization with polyvinyl alcohol particles was examined in 22 patients with islet cell carcinoma metastatic to the liver. Nine patients had gastrinoma, 2 had glucagonoma, and 11 had no discernible hormonal secretions or syndromes. Ninety-seven embolizations were done with a median number of 4 (range, 1 to 12) per patient. The interval between embolizations ranged from 1 to 8 months. Twelve of twenty evaluable patients had a partial remission, frequently associated with subjective improvement and decrease in hormone levels. The projected median survival of all 22 patients from the initiation of embolization is 33.7 months (range, 1 to 72). Nausea, vomiting, fever, and abdominal pain occurred with each embolization and subsided usually by day 10 (range, 3 to 35). Sequential hepatic artery occlusion is an effective method for prolonged palliation in this selected group of patients.
AB - The value of sequential percutaneous hepatic artery embolization with polyvinyl alcohol particles was examined in 22 patients with islet cell carcinoma metastatic to the liver. Nine patients had gastrinoma, 2 had glucagonoma, and 11 had no discernible hormonal secretions or syndromes. Ninety-seven embolizations were done with a median number of 4 (range, 1 to 12) per patient. The interval between embolizations ranged from 1 to 8 months. Twelve of twenty evaluable patients had a partial remission, frequently associated with subjective improvement and decrease in hormone levels. The projected median survival of all 22 patients from the initiation of embolization is 33.7 months (range, 1 to 72). Nausea, vomiting, fever, and abdominal pain occurred with each embolization and subsided usually by day 10 (range, 3 to 35). Sequential hepatic artery occlusion is an effective method for prolonged palliation in this selected group of patients.
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U2 - 10.7326/0003-4819-108-3-340
DO - 10.7326/0003-4819-108-3-340
M3 - Article
C2 - 2449109
AN - SCOPUS:0023926113
SN - 0003-4819
VL - 108
SP - 340
EP - 344
JO - Annals of internal medicine
JF - Annals of internal medicine
IS - 3
ER -