TY - JOUR
T1 - Isolation and characterization of early pregnancy factor.
AU - Zuo, X.
AU - Su, B.
AU - Wei, D.
N1 - Copyright:
This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
PY - 1994/3
Y1 - 1994/3
N2 - Early pregnancy factor (EPF) was purified from the pooled sera of 210 pregnant women at 3-8 weeks of gestation. Sera from healthy nonpregnant women were used as control. The samples (G-II, G-III and G-IV) obtained from pregnant women had EPF activity but no HCG activity. Polyacrylamide gel electrophoresis showed that the major bands in pregnant G-III and G-IV were at similar positions in tube gels. The results of SDS-PAGE showed 3 bands in pregnant G-IV: 57.0 kD, 38.0 kD and 19.0 kD. The basic active form of EPF may be a small peptide of 19.0 kD. The isoelectric points of pregnant G-IV were 6.45 and 8.20.
AB - Early pregnancy factor (EPF) was purified from the pooled sera of 210 pregnant women at 3-8 weeks of gestation. Sera from healthy nonpregnant women were used as control. The samples (G-II, G-III and G-IV) obtained from pregnant women had EPF activity but no HCG activity. Polyacrylamide gel electrophoresis showed that the major bands in pregnant G-III and G-IV were at similar positions in tube gels. The results of SDS-PAGE showed 3 bands in pregnant G-IV: 57.0 kD, 38.0 kD and 19.0 kD. The basic active form of EPF may be a small peptide of 19.0 kD. The isoelectric points of pregnant G-IV were 6.45 and 8.20.
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M3 - Article
C2 - 8086632
AN - SCOPUS:0028390517
SN - 1001-9294
VL - 9
SP - 34
EP - 37
JO - Chinese medical sciences journal = Chung-kuo i hsüeh k'o hsüeh tsa chih / Chinese Academy of Medical Sciences
JF - Chinese medical sciences journal = Chung-kuo i hsüeh k'o hsüeh tsa chih / Chinese Academy of Medical Sciences
IS - 1
ER -