Isolation and partial characterization of the human homologue of Thy-1

E. W. Ades; R. K. Zwerner; R. T. Acton; C. M. Balch

doi:10.1084/jem.151.2.400

Isolation and partial characterization of the human homologue of Thy-1

E. W. Ades, R. K. Zwerner, R. T. Acton, C. M. Balch

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Abstract

A glycoprotein of 25,000 daltons was isolated from a human T lymphoblastoid cell line (MOLT-3). A monovalent antiserum raised against this antigen precipitated mouse Thy-1.1 antigen as well as a 25,000-dalton antigen from human blood T cells. The unabsorbed serum was also cytotoxic for both mouse and human T cells. By multiple criteria, this human T antigen appears to be homologous with mouse Thy-1.

Original language	English (US)
Pages (from-to)	400-406
Number of pages	7
Journal	Journal of Experimental Medicine
Volume	151
Issue number	2
DOIs	https://doi.org/10.1084/jem.151.2.400
State	Published - 1980
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1084/jem.151.2.400

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abstract = "A glycoprotein of 25,000 daltons was isolated from a human T lymphoblastoid cell line (MOLT-3). A monovalent antiserum raised against this antigen precipitated mouse Thy-1.1 antigen as well as a 25,000-dalton antigen from human blood T cells. The unabsorbed serum was also cytotoxic for both mouse and human T cells. By multiple criteria, this human T antigen appears to be homologous with mouse Thy-1.",

author = "Ades, {E. W.} and Zwerner, {R. K.} and Acton, {R. T.} and Balch, {C. M.}",

year = "1980",

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AU - Ades, E. W.

AU - Zwerner, R. K.

AU - Acton, R. T.

AU - Balch, C. M.

PY - 1980

Y1 - 1980

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AB - A glycoprotein of 25,000 daltons was isolated from a human T lymphoblastoid cell line (MOLT-3). A monovalent antiserum raised against this antigen precipitated mouse Thy-1.1 antigen as well as a 25,000-dalton antigen from human blood T cells. The unabsorbed serum was also cytotoxic for both mouse and human T cells. By multiple criteria, this human T antigen appears to be homologous with mouse Thy-1.

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Isolation and partial characterization of the human homologue of Thy-1

Abstract

ASJC Scopus subject areas

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