It is time to include patients with brain tumors in phase I trials in oncology

Patrick Y. Wen, David Schiff, Timothy F. Cloughesy, David A. Reardon, Tracy T. Batchelor, Bruce A. Chabner, Keith Flaherty, John F. De Groot, Mark R. Gilbert, Evanthia Galanis, Susan M. Chang, Gary K. Schwartz, David Peereboom, Minesh P. Mehta, W. K.Alfred Yung, Stuart A. Grossman, Michael D. Prados, Lisa M. DeAngelis