@article{54de1a5faaf244fa8d839203578f2024,
title = "It's fun to transcribe with Fun30: A model for nucleosome dynamics during RNA polymerase II-mediated elongation",
abstract = "The ability of elongating RNA polymerase II (RNAPII) to regulate the nucleosome barrier is poorly understood because we do not know enough about the involved factors and we lack a conceptual framework to model this process. Our group recently identified the conserved Fun30/SMARCAD1 family chromatin-remodeling factor, Fun30Fft3, as being critical for relieving the nucleosome barrier during RNAPII-mediated elongation, and proposed a model illustrating how Fun30Fft3 may contribute to nucleosome disassembly during RNAPII-mediated elongation. Here, we present a model that describes nucleosome dynamics during RNAPII-mediated elongation in mathematical terms and addresses the involvement of Fun30Fft3 in this process.",
keywords = "chromatin remodeler, Fun30, histone chaperone FACT, nucleosome barrier, nucleosome disassembly, RNAPII elongation",
author = "Junwoo Lee and Choi, {Eun Shik} and Daeyoup Lee",
note = "Funding Information: This work was supported by grants from the Mid-career Researcher Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, and Future Planning (2016R1A2B2006354) and Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2012R1A1A2008564). Funding Information: This work was supported by grants from the Mid-career Researcher Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, and Future Planning (2016R1A2B2006354) and Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2012R1A1A2008564). We are grateful to Dr. Keunsoo Kang (Dankook University) for providing advice on our genome-wide analyses. Publisher Copyright: {\textcopyright} 2018, {\textcopyright} 2017 Taylor & Francis.",
year = "2018",
month = mar,
day = "15",
doi = "10.1080/21541264.2017.1356434",
language = "English (US)",
volume = "9",
pages = "108--116",
journal = "Transcription",
issn = "2154-1264",
publisher = "Friedrich-Berlin-Verlag",
number = "2",
}