Abstract
Juvenile chronic myelogenous leukemia (JCML) is a malignant hematopoietic disorder of monocyte-histiocyte lineage that affects children less than 4 years of age. Since the disease represents only 2% of all childhood leukemias, experience with it has been limited even in large centers. This review summarizes our 10 year institutional study of JCML as well as a comprehensive literature survey. The goal of the article is to underscore the cardinal features of juvenile chronic myelogenous leukemia that are useful for diagnosis, and to highlight recent advances in the understanding of the biology and treatment of the disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 261-267 |
| Number of pages | 7 |
| Journal | Journal of Pediatric Hematology/Oncology |
| Volume | 10 |
| Issue number | 3 |
| DOIs | |
| State | Published - 1988 |
Keywords
- Juvenile chronic myelogenous leukemia
- Treatment
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Hematology
- Oncology