Abstract
The transcription factor IRF-4 is necessary for Th17 cell differentiation. In this issue of Immunity, Chen et al. (2008) show that IRF-4-binding protein is a critical negative regulator of IRF-4 function, regulating production of the cytokines IL-21 and IL-17.
Original language | English (US) |
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Pages (from-to) | 841-843 |
Number of pages | 3 |
Journal | Immunity |
Volume | 29 |
Issue number | 6 |
DOIs | |
State | Published - Dec 19 2008 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Infectious Diseases