Keeping Autoimmunity in Check: How to Control a Th17 Cell Controller

Roza I. Nurieva, Chen Dong

Research output: Contribution to journalShort surveypeer-review

8 Scopus citations

Abstract

The transcription factor IRF-4 is necessary for Th17 cell differentiation. In this issue of Immunity, Chen et al. (2008) show that IRF-4-binding protein is a critical negative regulator of IRF-4 function, regulating production of the cytokines IL-21 and IL-17.

Original languageEnglish (US)
Pages (from-to)841-843
Number of pages3
JournalImmunity
Volume29
Issue number6
DOIs
StatePublished - Dec 19 2008

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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