TY - JOUR
T1 - Laparoscopic treatment of colorectal neoplasia
AU - Chang, George J.
N1 - Funding Information:
The final results from the National Cancer Institute-sponsored multi-institutional Clinical Outcomes of Surgical Therapy (COST) study were recently published [3•]. The COST study validated the oncologic efficacy of laparoscopy for colon cancer. Two additional large, multi-institutional trials are ongoing and should be reported soon: the Medical Research Council Conventional versus Laparoscopic-Assisted Surgery in Colorectal Cancer (CLASICC) trial in the United Kingdom [4] and the Colon Carcinoma Laparoscopic or Open Resection (COLOR) trial in Europe [5]. A number of smaller trials have also been reported. This review provides an overview of the operations and examines the data comparing the open with the laparoscopic approaches to colorectal cancer surgery, with emphasis on data from recent randomized controlled trials (RCTs).
PY - 2006/6
Y1 - 2006/6
N2 - A recent major advance in the surgical treatment of colorectal cancer has been the introduction of laparoscopic surgery. Laparoscopic colectomy is associated with decreased postoperative pain, faster ileus resolution, shorter hospital stay, improved cosmesis, and decreased morbidity when compared with open colectomy. However, early reports of high rates of laparoscopic wound metastases gave rise to questions regarding the adequacy of the laparoscopic technique for curative resection of malignancies. These concerns over oncologic outcomes are addressed by several single and mutti-institutional randomized trials in the United States and throughout the world that have compared laparoscopic-assisted colectomy with conventional open colectomy. These studies have established both the short- and long-term safety and oncologic efficacy of laparoscopic colectomy for cancer. To ensure successful outcomes, surgeons performing laparoscopic colectomy should be adequately experienced. Limitations include the technical requirements of advanced laparoscopic skills and training, increased operative time, and equipment costs. Despite these limitations, patient recovery benefits may offset the increased operative costs and result in improved outcome overall.
AB - A recent major advance in the surgical treatment of colorectal cancer has been the introduction of laparoscopic surgery. Laparoscopic colectomy is associated with decreased postoperative pain, faster ileus resolution, shorter hospital stay, improved cosmesis, and decreased morbidity when compared with open colectomy. However, early reports of high rates of laparoscopic wound metastases gave rise to questions regarding the adequacy of the laparoscopic technique for curative resection of malignancies. These concerns over oncologic outcomes are addressed by several single and mutti-institutional randomized trials in the United States and throughout the world that have compared laparoscopic-assisted colectomy with conventional open colectomy. These studies have established both the short- and long-term safety and oncologic efficacy of laparoscopic colectomy for cancer. To ensure successful outcomes, surgeons performing laparoscopic colectomy should be adequately experienced. Limitations include the technical requirements of advanced laparoscopic skills and training, increased operative time, and equipment costs. Despite these limitations, patient recovery benefits may offset the increased operative costs and result in improved outcome overall.
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U2 - 10.1007/s11938-006-0044-1
DO - 10.1007/s11938-006-0044-1
M3 - Review article
C2 - 16901389
AN - SCOPUS:33744948538
SN - 1092-8472
VL - 9
SP - 256
EP - 264
JO - Current Treatment Options in Gastroenterology
JF - Current Treatment Options in Gastroenterology
IS - 3
ER -