Late Effects after Autologous Hematopoietic Stem Cell Transplantation

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Autologous hematopoietic transplantation is now a well-established treatment for many malignant and nonmalignant disorders. Mobilization and collection of hematopoietic cells from peripheral blood with faster hematopoietic recovery has made this approach the treatment of choice for patients with relapsed lymphoma and standard of care for treatment of multiple myeloma. Of 50 000-60 000 hematopoietic stem cell transplants performed worldwide annually, 35 000-40 000 are autologous. With improvement in transplantation techniques, there are a growing number of autoHCT survivors as well as several late effects of transplantation that may account for decrease in long-term survival for recipients of autologous transplants.

Original languageEnglish (US)
Title of host publicationBlood and Marrow Transplantation Long Term Management
Subtitle of host publicationPrevention and Complications
PublisherWiley-Blackwell
Pages31-42
Number of pages12
ISBN (Electronic)9781118473306
ISBN (Print)9781118473405
DOIs
StatePublished - Sep 9 2013

Keywords

  • Chemotherapy-induced cardiomyopathy
  • Cognitive dysfunction
  • Endocrine dysfunction
  • Pulmonary toxicity
  • Secondary malignancy
  • Therapy-related acute myeloid leukemia

ASJC Scopus subject areas

  • General Medicine

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