TY - JOUR
T1 - Lessons Learned from the Impact of COVID-19 on NCI-sponsored Cancer Prevention Clinical Trials
T2 - Moving Toward Participant-centric Study Designs
AU - Samimi, Goli
AU - House, Margaret
AU - Benante, Kelly
AU - Bengtson, Lisa
AU - Budd, Troy
AU - Dermody, Bridget
AU - DeShong, Katina
AU - Dyer, Valerie
AU - Kimler, Bruce F.
AU - Sahasrabuddhe, Vikrant V.
AU - Siminski, Suzanne
AU - Ford, Leslie G.
AU - Vilar, Eduardo
AU - Szabo, Eva
N1 - Publisher Copyright:
© 2022 American Association for Cancer Research
PY - 2022/5
Y1 - 2022/5
N2 - The COVID-19 pandemic overloaded health care systems around the globe and brought travel restrictions and other mandates. These effects critically impacted cancer care and conduct of clinical trials, and required medical and research communities to incorporate changes and novel flexible work-flows within clinical trials and regulations to improve efficiency. We report the impact of the pandemic on cancer prevention clinical trials managed by the Division of Cancer Prevention within the NCI, focusing on participant-centric, study staff-centric and regulatory elements. Learning lessons from this challenging period, the cancer prevention community has the opportunity to incorporate many of these necessitated novel approaches to future design of clinical trials, to streamline and improve clinical trial efficiency and impact.
AB - The COVID-19 pandemic overloaded health care systems around the globe and brought travel restrictions and other mandates. These effects critically impacted cancer care and conduct of clinical trials, and required medical and research communities to incorporate changes and novel flexible work-flows within clinical trials and regulations to improve efficiency. We report the impact of the pandemic on cancer prevention clinical trials managed by the Division of Cancer Prevention within the NCI, focusing on participant-centric, study staff-centric and regulatory elements. Learning lessons from this challenging period, the cancer prevention community has the opportunity to incorporate many of these necessitated novel approaches to future design of clinical trials, to streamline and improve clinical trial efficiency and impact.
UR - http://www.scopus.com/inward/record.url?scp=85129447772&partnerID=8YFLogxK
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U2 - 10.1158/1940-6207.CAPR-21-0578
DO - 10.1158/1940-6207.CAPR-21-0578
M3 - Review article
C2 - 35502553
AN - SCOPUS:85129447772
SN - 1940-6207
VL - 15
SP - 279
EP - 284
JO - Cancer Prevention Research
JF - Cancer Prevention Research
IS - 5
ER -