Levels of plasma soluble complement receptor 1 (sCR1) in normal indian adult population

B. Sivasankar, K. R. Raju, V. Anand, S. Malu, S. Padmanabhan, S. C. Tiwari, Nibhriti Das, L. M. Srivastava.

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A decrease in the membrane anchored erythrocyte complement receptor 1 (CR1) is reported as an acquired phenomenon in a number of inflammatory and autoimmune diseases with concomitant rise in soluble CR1 (sCR1) levels in plasma. There is a need to establish the normal range of sCR1 in Indian adults to assess the function and disease association of this protein.The plasma sCR1 levels of SO healthy individuals have been estimated by an indigenously developed sandwich ELISA. sCR1 levels from 26 patients suffering from nephropathies had also been assayed which was much higher than the normal controls.This observation suggests sCR1 as a potential marker for the assessment of disease activity in nephropathies.

Original languageEnglish (US)
Pages (from-to)237-240
Number of pages4
JournalIndian Journal of Clinical Biochemistry
Volume14
Issue number2
DOIs
StatePublished - 1999

Keywords

  • Prognostic marker
  • Renal diseases
  • Soluble complement receptor 1

ASJC Scopus subject areas

  • Clinical Biochemistry

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