Abstract
A decrease in the membrane anchored erythrocyte complement receptor 1 (CR1) is reported as an acquired phenomenon in a number of inflammatory and autoimmune diseases with concomitant rise in soluble CR1 (sCR1) levels in plasma. There is a need to establish the normal range of sCR1 in Indian adults to assess the function and disease association of this protein.The plasma sCR1 levels of SO healthy individuals have been estimated by an indigenously developed sandwich ELISA. sCR1 levels from 26 patients suffering from nephropathies had also been assayed which was much higher than the normal controls.This observation suggests sCR1 as a potential marker for the assessment of disease activity in nephropathies.
Original language | English (US) |
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Pages (from-to) | 237-240 |
Number of pages | 4 |
Journal | Indian Journal of Clinical Biochemistry |
Volume | 14 |
Issue number | 2 |
DOIs | |
State | Published - 1999 |
Keywords
- Prognostic marker
- Renal diseases
- Soluble complement receptor 1
ASJC Scopus subject areas
- Clinical Biochemistry