Liquid Biopsy as an Adjunct to Lung Screening Imaging

Nathaniel Deboever; Edwin Justin Ostrin; Mara B. Antonoff

doi:10.1016/j.thorsurg.2023.04.004

Liquid Biopsy as an Adjunct to Lung Screening Imaging

Nathaniel Deboever, Edwin Justin Ostrin, Mara B. Antonoff

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Current lung cancer screening protocols use low-dose computed tomography scans in selected high-risk individuals. Unfortunately, utilization is low, and the rate of false-positive screens is high. Peripheral biomarkers carry meaningful promise in diagnosing and monitoring cancer with added potential advantages reducing invasive procedures and improving turnaround time. Herein, the use of such blood-based assays is considered as an adjunct to further utilization and accuracy of lung cancer screening.

Original language	English (US)
Pages (from-to)	411-419
Number of pages	9
Journal	Thoracic surgery clinics
Volume	33
Issue number	4
DOIs	https://doi.org/10.1016/j.thorsurg.2023.04.004
State	Published - Nov 1 2023

Keywords

Disease monitoring
Liquid biopsy
Low-dose computed tomography scan
Lung cancer screening

ASJC Scopus subject areas

General Medicine

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10.1016/j.thorsurg.2023.04.004

Cite this

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title = "Liquid Biopsy as an Adjunct to Lung Screening Imaging",

abstract = "Current lung cancer screening protocols use low-dose computed tomography scans in selected high-risk individuals. Unfortunately, utilization is low, and the rate of false-positive screens is high. Peripheral biomarkers carry meaningful promise in diagnosing and monitoring cancer with added potential advantages reducing invasive procedures and improving turnaround time. Herein, the use of such blood-based assays is considered as an adjunct to further utilization and accuracy of lung cancer screening.",

keywords = "Disease monitoring, Liquid biopsy, Low-dose computed tomography scan, Lung cancer screening",

author = "Nathaniel Deboever and Ostrin, {Edwin Justin} and Antonoff, {Mara B.}",

year = "2023",

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T1 - Liquid Biopsy as an Adjunct to Lung Screening Imaging

AU - Deboever, Nathaniel

AU - Ostrin, Edwin Justin

AU - Antonoff, Mara B.

PY - 2023/11/1

Y1 - 2023/11/1

N2 - Current lung cancer screening protocols use low-dose computed tomography scans in selected high-risk individuals. Unfortunately, utilization is low, and the rate of false-positive screens is high. Peripheral biomarkers carry meaningful promise in diagnosing and monitoring cancer with added potential advantages reducing invasive procedures and improving turnaround time. Herein, the use of such blood-based assays is considered as an adjunct to further utilization and accuracy of lung cancer screening.

AB - Current lung cancer screening protocols use low-dose computed tomography scans in selected high-risk individuals. Unfortunately, utilization is low, and the rate of false-positive screens is high. Peripheral biomarkers carry meaningful promise in diagnosing and monitoring cancer with added potential advantages reducing invasive procedures and improving turnaround time. Herein, the use of such blood-based assays is considered as an adjunct to further utilization and accuracy of lung cancer screening.

KW - Disease monitoring

KW - Liquid biopsy

KW - Low-dose computed tomography scan

KW - Lung cancer screening

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DO - 10.1016/j.thorsurg.2023.04.004

M3 - Review article

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AN - SCOPUS:85173337091

SN - 1547-4127

VL - 33

SP - 411

EP - 419

JO - Thoracic surgery clinics

JF - Thoracic surgery clinics

IS - 4

ER -

Liquid Biopsy as an Adjunct to Lung Screening Imaging

Abstract

Keywords

ASJC Scopus subject areas

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