Abstract
In situ hybridization was used to localize the sites of the repeated sequences of cytoplasmic membrane associated DNA (cmDNA) in human chromosomes. cmDNA was mainly present in the heterochromatic regions of chromosomes 9. Although cmDNA has buoyant densities in neutral and alkaline CsCl gradients similar to those of human satellite CDNA, which also is localized in the heterochromatic region of chromosomes 9, cm DNA was not homologous to satellite CDNA as determined by DNA complementary RNA hybridization. These results are in agreement with previous studies, which indicated that cmDNA is a unique species of human DNA.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 5004-5006 |
| Number of pages | 3 |
| Journal | Proceedings of the National Academy of Sciences of the United States of America |
| Volume | 72 |
| Issue number | 12 |
| DOIs | |
| State | Published - 1975 |
ASJC Scopus subject areas
- General