Locally advanced breast cancer

F. J. Esteva; G. N. Hortobagyi

doi:10.1016/S0889-8588(05)70065-4

Locally advanced breast cancer

F. J. Esteva, G. N. Hortobagyi

Breast Medical Oncology

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

The multidisciplinary management of patients with locally advanced breast cancer (LABC) has evolved over the last three decades. The introduction of chemotherapy (CT) and endocrine therapy in conjunction with surgery and radiation therapy (XRT) have changed the natural history of this disease. The authors discuss the role of the taxanes, novel endocrine therapy, and high-dose CT programs in the management of LABC. Indications for breast-conserving surgery are presented. The role of prognostic and predictive tumor markers in LABC is discussed.

Original language	English (US)
Pages (from-to)	457-472
Number of pages	16
Journal	Hematology/Oncology Clinics of North America
Volume	13
Issue number	2
DOIs	https://doi.org/10.1016/S0889-8588(05)70065-4
State	Published - 1999

ASJC Scopus subject areas

Hematology
Oncology

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10.1016/S0889-8588(05)70065-4

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AB - The multidisciplinary management of patients with locally advanced breast cancer (LABC) has evolved over the last three decades. The introduction of chemotherapy (CT) and endocrine therapy in conjunction with surgery and radiation therapy (XRT) have changed the natural history of this disease. The authors discuss the role of the taxanes, novel endocrine therapy, and high-dose CT programs in the management of LABC. Indications for breast-conserving surgery are presented. The role of prognostic and predictive tumor markers in LABC is discussed.

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Locally advanced breast cancer

Abstract

ASJC Scopus subject areas

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