TY - JOUR
T1 - Low-grade epithelial ovarian cancer
T2 - What a radiologist should know
AU - Elsherif, Sherif
AU - Javadi, Sanaz
AU - Viswanathan, Chitra
AU - Faria, Silvana
AU - Bhosale, Priya
N1 - Publisher Copyright:
© 2019 The Authors. Published by the British Institute of Radiology
PY - 2019
Y1 - 2019
N2 - Ovarian cancer accounts for the death of over 100,000 females every year and is the most lethal gynecological malignancy. Low-grade serous ovarian carcinoma (LGSOC) and high-grade serous ovarian carcinoma (HGSOC) have been found to represent two distinct entities based on their molecular differences, clinical course, and response to chemotherapy. Currently, all ovarian cancers are staged according to the revised staging system of the International Federation of Gynecology and Obstetrics (FIGO). Imaging plays an integral role in the diagnosis, staging, and follow-up of ovarian cancers. This review will be based on the two-tier grading system of epithelial ovarian cancers, with the main emphasis on serous ovarian cancer, and the role of imaging to characterize low-grade vs high-grade tumors and monitor disease recurrence during follow-up.
AB - Ovarian cancer accounts for the death of over 100,000 females every year and is the most lethal gynecological malignancy. Low-grade serous ovarian carcinoma (LGSOC) and high-grade serous ovarian carcinoma (HGSOC) have been found to represent two distinct entities based on their molecular differences, clinical course, and response to chemotherapy. Currently, all ovarian cancers are staged according to the revised staging system of the International Federation of Gynecology and Obstetrics (FIGO). Imaging plays an integral role in the diagnosis, staging, and follow-up of ovarian cancers. This review will be based on the two-tier grading system of epithelial ovarian cancers, with the main emphasis on serous ovarian cancer, and the role of imaging to characterize low-grade vs high-grade tumors and monitor disease recurrence during follow-up.
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U2 - 10.1259/bjr.20180571
DO - 10.1259/bjr.20180571
M3 - Review article
C2 - 30604635
AN - SCOPUS:85061963805
SN - 0007-1285
VL - 92
JO - British Journal of Radiology
JF - British Journal of Radiology
IS - 1095
M1 - 20180571
ER -