Low infectivity among asymptomatic patients with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) admission test at a tertiary care center, 2020-2022

Jane W. Liang; Melanie A. Kiener; Gustavo Contreras; Guillermo Rodriguez-Nava; Alex N. Zimmet; Caitlin A. Contag; Krithika Srinivasan; Karen McIntyre; Aruna Subramanian; John Shepard; Lucy S. Tompkins; Benjamin A. Pinsky; Jorge L. Salinas

doi:10.1017/ice.2023.210

Low infectivity among asymptomatic patients with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) admission test at a tertiary care center, 2020-2022

Jane W. Liang, Melanie A. Kiener, Gustavo Contreras, Guillermo Rodriguez-Nava, Alex N. Zimmet, Caitlin A. Contag, Krithika Srinivasan, Karen McIntyre, Aruna Subramanian, John Shepard, Lucy S. Tompkins, Benjamin A. Pinsky, Jorge L. Salinas

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We used a strand-specific RT-qPCR to evaluate viral replication as a surrogate for infectiousness among 242 asymptomatic inpatients with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) admission test. Only 21 patients (9%) had detectable SARS-CoV-2 minus-strand RNA. Because most patients were found to be noninfectious, our findings support the suspension of asymptomatic admission testing.

Original language	English (US)
Pages (from-to)	241-243
Number of pages	3
Journal	Infection Control and Hospital Epidemiology
Volume	45
Issue number	2
DOIs	https://doi.org/10.1017/ice.2023.210
State	Published - Feb 25 2024
Externally published	Yes

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

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10.1017/ice.2023.210

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Liang, J. W., Kiener, M. A., Contreras, G., Rodriguez-Nava, G., Zimmet, A. N., Contag, C. A., Srinivasan, K., McIntyre, K., Subramanian, A., Shepard, J., Tompkins, L. S., Pinsky, B. A., & Salinas, J. L. (2024). Low infectivity among asymptomatic patients with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) admission test at a tertiary care center, 2020-2022. Infection Control and Hospital Epidemiology, 45(2), 241-243. https://doi.org/10.1017/ice.2023.210

Low infectivity among asymptomatic patients with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) admission test at a tertiary care center, 2020-2022. / Liang, Jane W.; Kiener, Melanie A.; Contreras, Gustavo et al.
In: Infection Control and Hospital Epidemiology, Vol. 45, No. 2, 25.02.2024, p. 241-243.

Research output: Contribution to journal › Article › peer-review

Liang, JW, Kiener, MA, Contreras, G, Rodriguez-Nava, G, Zimmet, AN, Contag, CA, Srinivasan, K, McIntyre, K, Subramanian, A, Shepard, J, Tompkins, LS, Pinsky, BA & Salinas, JL 2024, 'Low infectivity among asymptomatic patients with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) admission test at a tertiary care center, 2020-2022', Infection Control and Hospital Epidemiology, vol. 45, no. 2, pp. 241-243. https://doi.org/10.1017/ice.2023.210

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Low infectivity among asymptomatic patients with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) admission test at a tertiary care center, 2020-2022

Abstract

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