TY - JOUR
T1 - Lymphocyte recovery and infused CD34+ cells dose
T2 - Effect on the evolution after stem cell autotransplantation
AU - Romero Fernández, Esperanza
AU - Bravo, Guillermo Montalbán
AU - Gallastegui, Rosario Arrieta
AU - De la Rúa Fernández, Ana Rodríguez
PY - 2013
Y1 - 2013
N2 - Background and objective: The number of infused CD34+cells (CD34+. i) has been associated with absolute lymphocyte count (ALC) and the outcome undergoing autologous hematopoietic stem cell transplantation (HSCT) in patients with hematologic malignancies. The study's aim was to analyze the relationship between CD34+. i, ALC and prognosis in this patients. Patients and method: Medical records of 163 patients receiving HSCT between 2005 and 2012 were reviewed. Results: We found significant and inversely proportional relationship between the CD34+. i and the days required to reach ALC≥500/μl according to the regression line: days=-0.981×number of CD34+. i+18.09. Conclusions: We have obtained a predictive model of lymphocyte recovery based recovery of CD34+. i.
AB - Background and objective: The number of infused CD34+cells (CD34+. i) has been associated with absolute lymphocyte count (ALC) and the outcome undergoing autologous hematopoietic stem cell transplantation (HSCT) in patients with hematologic malignancies. The study's aim was to analyze the relationship between CD34+. i, ALC and prognosis in this patients. Patients and method: Medical records of 163 patients receiving HSCT between 2005 and 2012 were reviewed. Results: We found significant and inversely proportional relationship between the CD34+. i and the days required to reach ALC≥500/μl according to the regression line: days=-0.981×number of CD34+. i+18.09. Conclusions: We have obtained a predictive model of lymphocyte recovery based recovery of CD34+. i.
KW - Infused CD34+ cells
KW - Inmune reconstitution
KW - Lymphocyte recovery
KW - Prognosis
KW - Stem cell autotransplantation
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U2 - 10.1016/j.lrr.2013.06.002
DO - 10.1016/j.lrr.2013.06.002
M3 - Article
C2 - 24371781
AN - SCOPUS:84887933002
SN - 2213-0489
VL - 2
SP - 54
EP - 57
JO - Leukemia Research Reports
JF - Leukemia Research Reports
IS - 2
ER -