Macrocycles as a tool: A facile and one-pot synthesis of silver nanoparticles using cucurbituril designed for cancer therapeutics

Thathan Premkumar; Yeonju Lee; Kurt E. Geckeler

doi:10.1002/chem.201001325

Macrocycles as a tool: A facile and one-pot synthesis of silver nanoparticles using cucurbituril designed for cancer therapeutics

Thathan Premkumar, Yeonju Lee, Kurt E. Geckeler

Radiation Oncology

Research output: Contribution to journal › Article › peer-review

64 Scopus citations

Abstract

Silver nanoparticles made easy: A simple, effective, and one-pot method toward the synthesis of a defined macrocycle-silver nanoparticle system in water has been described (see figure). Interestingly, cucurbituril (CB)[7]-protected AgNPs showed significantly increased cytotoxicity against MCF-7 and NCI-H358 cancer cells, as demonstrated by models in vitro.

Original language	English (US)
Pages (from-to)	11563-11566
Number of pages	4
Journal	Chemistry - A European Journal
Volume	16
Issue number	38
DOIs	https://doi.org/10.1002/chem.201001325
State	Published - Oct 11 2010

Keywords

Biomedical applications
Cucurbiturils cytotoxicity
Nanoparticles
Silver

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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10.1002/chem.201001325

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Macrocycles as a tool: A facile and one-pot synthesis of silver nanoparticles using cucurbituril designed for cancer therapeutics

Abstract

Keywords

ASJC Scopus subject areas

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