Management of liver metastases from colorectal cancer

Junichi Shindoh, Giuseppe Zimmitti, Jean Nicolas Vauthey

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

With recent advances in chemotherapy and surgery, resectability of colorectal liver metastases (CLM) has dramatically increased and 5-year survival has significantly improved. In this chapter, we review the evaluation, treatment, and outcome of patients treated with surgery for colorectal liver metastases. Methods to improve resectability (portal vein embolization and two-stage resection) are reviewed. Major pathologic response, optimal radiologic response, and RAS tumor predict improved 5-year survival after resection in patients treated preoperatively with modern chemotherapy.

Original languageEnglish (US)
Title of host publicationSurgical Oncology a Practical and Comprehensive Approach
PublisherSpringer New York
Pages449-461
Number of pages13
ISBN (Electronic)9781493914234
ISBN (Print)9781493914227
DOIs
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • General Medicine

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