Management of perioperative anticoagulation in a patient with antiphospholipid antibody syndrome undergoing cardiac surgery: A case report

Sanjana A. Malviya; Yi Deng; Sayyed O. Gilani; Alec A. Hendon; Melissa A. Nikolaidis; Micah S. Moseley

doi:10.4103/aca.aca_228_20

Management of perioperative anticoagulation in a patient with antiphospholipid antibody syndrome undergoing cardiac surgery: A case report

Sanjana A. Malviya, Yi Deng, Sayyed O. Gilani, Alec A. Hendon, Melissa A. Nikolaidis, Micah S. Moseley

Research output: Contribution to journal › Article › peer-review

Abstract

Patients with Antiphospholipid syndrome (APLS) are at high risk for both bleeding and thrombotic complications during cardiac surgery involving cardiopulmonary bypass (CPB). In this case we present a patient with APLS and Immune Thrombocytopenic Purpura who successfully underwent aortic valve replacement (AVR) with CPB despite recent craniotomy for subdural hematoma evacuation. Anticoagulation for CPB was monitored by targeting an Activated Clotting Time (ACT) that was 2× the upper limit of normal. A multidisciplinary approach was essential in ensuring a safe and successful operation.

Original language	English (US)
Pages (from-to)	206-209
Number of pages	4
Journal	Annals of Cardiac Anaesthesia
Volume	25
Issue number	2
DOIs	https://doi.org/10.4103/aca.aca_228_20
State	Published - Apr 1 2022
Externally published	Yes

Keywords

Antifibrinolytics
antiphospholipid syndrome
cardiopulmonary bypass
immune thrombocytopenic purpura
Libman-Sacks endocarditis

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Anesthesiology and Pain Medicine

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10.4103/aca.aca_228_20

Cite this

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abstract = "Patients with Antiphospholipid syndrome (APLS) are at high risk for both bleeding and thrombotic complications during cardiac surgery involving cardiopulmonary bypass (CPB). In this case we present a patient with APLS and Immune Thrombocytopenic Purpura who successfully underwent aortic valve replacement (AVR) with CPB despite recent craniotomy for subdural hematoma evacuation. Anticoagulation for CPB was monitored by targeting an Activated Clotting Time (ACT) that was 2× the upper limit of normal. A multidisciplinary approach was essential in ensuring a safe and successful operation.",

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AU - Gilani, Sayyed O.

AU - Hendon, Alec A.

AU - Nikolaidis, Melissa A.

AU - Moseley, Micah S.

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AB - Patients with Antiphospholipid syndrome (APLS) are at high risk for both bleeding and thrombotic complications during cardiac surgery involving cardiopulmonary bypass (CPB). In this case we present a patient with APLS and Immune Thrombocytopenic Purpura who successfully underwent aortic valve replacement (AVR) with CPB despite recent craniotomy for subdural hematoma evacuation. Anticoagulation for CPB was monitored by targeting an Activated Clotting Time (ACT) that was 2× the upper limit of normal. A multidisciplinary approach was essential in ensuring a safe and successful operation.

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Management of perioperative anticoagulation in a patient with antiphospholipid antibody syndrome undergoing cardiac surgery: A case report

Abstract

Keywords

ASJC Scopus subject areas

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