Management of recurrent colorectal cancer: Another look at carcinoembryonic antigen-detected recurrence

J. Nicolas Vauthey, Paul S. Dudrick, D. Scott Lind, Edward M. Copeland

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

There is currently controversy regarding the use of serum carcinoembryonic antigen (CEA) in the follow-up of colorectal cancer. This article reviews the most recent clinical data regarding CEA and discusses the rationales for its use in the follow-up of colorectal cancer. The patterns of colorectal cancer recurrence and their variable association with CEA elevation are presented. The contributions of the new imaging modalities, including radiolabeled antibodies, are reviewed end information on the prognosis following resection of recurrences is provided. A practical approach to colorectal cancer recurrences is suggested in two algorithms.

Original languageEnglish (US)
Pages (from-to)5-13
Number of pages9
JournalDigestive Diseases
Volume14
Issue number1
DOIs
StatePublished - 1996
Externally publishedYes

Keywords

  • Carcinoembryonic antigen
  • Colon cancer
  • Follow-up, colorectal cancer
  • Prognosis, colorectal cancer
  • Recurrence, colorectal cancer

ASJC Scopus subject areas

  • Gastroenterology

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