Mechanism of human immunodeficiency virus type I entry into the target cells

Yinghua Chen; Yi Xiao; Manfred P. Dierich

Mechanism of human immunodeficiency virus type I entry into the target cells

Yinghua Chen, Yi Xiao, Manfred P. Dierich

Research output: Contribution to journal › Article › peer-review

Abstract

Based on the recent advances of the research on the mechanism of HIV-1 infection, a novel model to elucidate the mechanism of HIV entry into the target cells is proposed and the perspective about the putative receptor is discussed in this review. Understanding of the crystal structure of HIV-1 transmembrane protein gp41 and the functions of HIV-1 receptor, co-receptor and the putative receptor will lead to developing effective HIV vaccine and anti-HIV drugs.

Original language	English (US)
Pages (from-to)	93-95
Number of pages	3
Journal	Progress in Natural Science
Volume	10
Issue number	2
State	Published - 2000
Externally published	Yes

Keywords

Envelope protein
HIV entry
HIV-1 receptor
Target cells

ASJC Scopus subject areas

General Materials Science

Cite this

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title = "Mechanism of human immunodeficiency virus type I entry into the target cells",

abstract = "Based on the recent advances of the research on the mechanism of HIV-1 infection, a novel model to elucidate the mechanism of HIV entry into the target cells is proposed and the perspective about the putative receptor is discussed in this review. Understanding of the crystal structure of HIV-1 transmembrane protein gp41 and the functions of HIV-1 receptor, co-receptor and the putative receptor will lead to developing effective HIV vaccine and anti-HIV drugs.",

keywords = "Envelope protein, HIV entry, HIV-1 receptor, Target cells",

author = "Yinghua Chen and Yi Xiao and Dierich, {Manfred P.}",

year = "2000",

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T1 - Mechanism of human immunodeficiency virus type I entry into the target cells

AU - Chen, Yinghua

AU - Xiao, Yi

AU - Dierich, Manfred P.

PY - 2000

Y1 - 2000

N2 - Based on the recent advances of the research on the mechanism of HIV-1 infection, a novel model to elucidate the mechanism of HIV entry into the target cells is proposed and the perspective about the putative receptor is discussed in this review. Understanding of the crystal structure of HIV-1 transmembrane protein gp41 and the functions of HIV-1 receptor, co-receptor and the putative receptor will lead to developing effective HIV vaccine and anti-HIV drugs.

AB - Based on the recent advances of the research on the mechanism of HIV-1 infection, a novel model to elucidate the mechanism of HIV entry into the target cells is proposed and the perspective about the putative receptor is discussed in this review. Understanding of the crystal structure of HIV-1 transmembrane protein gp41 and the functions of HIV-1 receptor, co-receptor and the putative receptor will lead to developing effective HIV vaccine and anti-HIV drugs.

KW - Envelope protein

KW - HIV entry

KW - HIV-1 receptor

KW - Target cells

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M3 - Article

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Mechanism of human immunodeficiency virus type I entry into the target cells

Abstract

Keywords

ASJC Scopus subject areas

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