Medullary Thyroid Cancer

Y. Nancy You; Vipul Lakhani; Samuel A. Wells; Jeffrey F. Moley

doi:10.1016/j.soc.2006.05.008

Medullary Thyroid Cancer

Y. Nancy You, Vipul Lakhani, Samuel A. Wells, Jeffrey F. Moley

Research output: Contribution to journal › Review article › peer-review

33 Scopus citations

Abstract

The goal in managing patients who have MTC is to detect and surgically remove disease at an early stage. Tumor marker-based biochemical screening and DNA-based genetic screening have created the opportunity for effective prophylactic surgery in patients at risk for hereditary MTC. Complete surgical resection is critical for cure because cervical reoperation for persistent or recurrent disease benefits only select patients. With the advent of therapies that target the RET-activated pathways, new hope may be emerging for patients who have locally advanced or metastatic disease.

Original language	English (US)
Pages (from-to)	639-660
Number of pages	22
Journal	Surgical oncology clinics of North America
Volume	15
Issue number	3
DOIs	https://doi.org/10.1016/j.soc.2006.05.008
State	Published - Jul 2006
Externally published	Yes

ASJC Scopus subject areas

Surgery
Oncology

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10.1016/j.soc.2006.05.008

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title = "Medullary Thyroid Cancer",

abstract = "The goal in managing patients who have MTC is to detect and surgically remove disease at an early stage. Tumor marker-based biochemical screening and DNA-based genetic screening have created the opportunity for effective prophylactic surgery in patients at risk for hereditary MTC. Complete surgical resection is critical for cure because cervical reoperation for persistent or recurrent disease benefits only select patients. With the advent of therapies that target the RET-activated pathways, new hope may be emerging for patients who have locally advanced or metastatic disease.",

author = "You, {Y. Nancy} and Vipul Lakhani and Wells, {Samuel A.} and Moley, {Jeffrey F.}",

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AU - Wells, Samuel A.

AU - Moley, Jeffrey F.

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AB - The goal in managing patients who have MTC is to detect and surgically remove disease at an early stage. Tumor marker-based biochemical screening and DNA-based genetic screening have created the opportunity for effective prophylactic surgery in patients at risk for hereditary MTC. Complete surgical resection is critical for cure because cervical reoperation for persistent or recurrent disease benefits only select patients. With the advent of therapies that target the RET-activated pathways, new hope may be emerging for patients who have locally advanced or metastatic disease.

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Medullary Thyroid Cancer

Abstract

ASJC Scopus subject areas

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