Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities

Zeynep Eroglu; Sheri L. Holmen; Qing Chen; Nikhil I. Khushalani; Ravi Amaravadi; Reena Thomas; Kamran A. Ahmed; Hussein Tawbi; Sunandana Chandra; Joseph Markowitz; Inna Smalley; James K.C. Liu; Yian Ann Chen; Yana G. Najjar; Florian A. Karreth; Daniel Abate-Daga; Isabella C. Glitza; Jeffrey A. Sosman; Vernon K. Sondak; Marcus Bosenberg; Meenhard Herlyn; Michael B. Atkins; Harriet Kluger; Kim Margolin; Peter A. Forsyth; Michael A. Davies; Keiran S.M. Smalley

doi:10.1111/pcmr.12771

Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities

Zeynep Eroglu, Sheri L. Holmen, Qing Chen, Nikhil I. Khushalani, Ravi Amaravadi, Reena Thomas, Kamran A. Ahmed, Hussein Tawbi, Sunandana Chandra, Joseph Markowitz, Inna Smalley, James K.C. Liu, Yian Ann Chen, Yana G. Najjar, Florian A. Karreth, Daniel Abate-Daga, Isabella C. Glitza, Jeffrey A. Sosman, Vernon K. Sondak, Marcus BosenbergMeenhard Herlyn, Michael B. Atkins, Harriet Kluger, Kim Margolin, Peter A. Forsyth, Michael A. Davies, Keiran S.M. Smalley

Melanoma Medical Oncology

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

In February 2018, the Melanoma Research Foundation and the Moffitt Cancer Center hosted the Second Summit on Melanoma Central Nervous System (CNS) Metastases in Tampa, Florida. In this white paper, we outline the current status of basic science, translational, and clinical research into melanoma brain metastasis development and therapeutic management. We further outline the important challenges that remain for the field and the critical barriers that need to be overcome for continued progress to be made in this clinically difficult area.

Original language	English (US)
Pages (from-to)	458-469
Number of pages	12
Journal	Pigment Cell and Melanoma Research
Volume	32
Issue number	3
DOIs	https://doi.org/10.1111/pcmr.12771
State	Published - May 2019

Keywords

brain metastases
immunotherapy
melanoma
metastasis
targeted therapy

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
Oncology
Dermatology

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10.1111/pcmr.12771

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Eroglu, Z., Holmen, S. L., Chen, Q., Khushalani, N. I., Amaravadi, R., Thomas, R., Ahmed, K. A., Tawbi, H., Chandra, S., Markowitz, J., Smalley, I., Liu, J. K. C., Chen, Y. A., Najjar, Y. G., Karreth, F. A., Abate-Daga, D., Glitza, I. C., Sosman, J. A., Sondak, V. K., ... Smalley, K. S. M. (2019). Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities. Pigment Cell and Melanoma Research, 32(3), 458-469. https://doi.org/10.1111/pcmr.12771

Eroglu, Z, Holmen, SL, Chen, Q, Khushalani, NI, Amaravadi, R, Thomas, R, Ahmed, KA, Tawbi, H, Chandra, S, Markowitz, J, Smalley, I, Liu, JKC, Chen, YA, Najjar, YG, Karreth, FA, Abate-Daga, D, Glitza, IC, Sosman, JA, Sondak, VK, Bosenberg, M, Herlyn, M, Atkins, MB, Kluger, H, Margolin, K, Forsyth, PA, Davies, MA & Smalley, KSM 2019, 'Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities', Pigment Cell and Melanoma Research, vol. 32, no. 3, pp. 458-469. https://doi.org/10.1111/pcmr.12771

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title = "Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities",

abstract = "In February 2018, the Melanoma Research Foundation and the Moffitt Cancer Center hosted the Second Summit on Melanoma Central Nervous System (CNS) Metastases in Tampa, Florida. In this white paper, we outline the current status of basic science, translational, and clinical research into melanoma brain metastasis development and therapeutic management. We further outline the important challenges that remain for the field and the critical barriers that need to be overcome for continued progress to be made in this clinically difficult area.",

keywords = "brain metastases, immunotherapy, melanoma, metastasis, targeted therapy",

author = "Zeynep Eroglu and Holmen, {Sheri L.} and Qing Chen and Khushalani, {Nikhil I.} and Ravi Amaravadi and Reena Thomas and Ahmed, {Kamran A.} and Hussein Tawbi and Sunandana Chandra and Joseph Markowitz and Inna Smalley and Liu, {James K.C.} and Chen, {Yian Ann} and Najjar, {Yana G.} and Karreth, {Florian A.} and Daniel Abate-Daga and Glitza, {Isabella C.} and Sosman, {Jeffrey A.} and Sondak, {Vernon K.} and Marcus Bosenberg and Meenhard Herlyn and Atkins, {Michael B.} and Harriet Kluger and Kim Margolin and Forsyth, {Peter A.} and Davies, {Michael A.} and Smalley, {Keiran S.M.}",

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year = "2019",

month = may,

doi = "10.1111/pcmr.12771",

language = "English (US)",

volume = "32",

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AU - Eroglu, Zeynep

AU - Holmen, Sheri L.

AU - Chen, Qing

AU - Khushalani, Nikhil I.

AU - Amaravadi, Ravi

AU - Thomas, Reena

AU - Ahmed, Kamran A.

AU - Tawbi, Hussein

AU - Chandra, Sunandana

AU - Markowitz, Joseph

AU - Smalley, Inna

AU - Liu, James K.C.

AU - Chen, Yian Ann

AU - Najjar, Yana G.

AU - Karreth, Florian A.

AU - Abate-Daga, Daniel

AU - Glitza, Isabella C.

AU - Sosman, Jeffrey A.

AU - Sondak, Vernon K.

AU - Bosenberg, Marcus

AU - Herlyn, Meenhard

AU - Atkins, Michael B.

AU - Kluger, Harriet

AU - Margolin, Kim

AU - Forsyth, Peter A.

AU - Davies, Michael A.

AU - Smalley, Keiran S.M.

PY - 2019/5

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KW - immunotherapy

KW - melanoma

KW - metastasis

KW - targeted therapy

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Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities

Abstract

Keywords

ASJC Scopus subject areas

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