TY - JOUR
T1 - Merkel cell carcinoma with gastric metastasis and review of literature
AU - Hu, Zishuo Ian
AU - Schuster, Jessica A.
AU - Kudelka, Andrzej P.
AU - Huston, Tara L.
N1 - Publisher Copyright:
© The Author(s) 2015.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - Background: Merkel cell carcinoma (MCC) is a rare, highly aggressive cutaneous neoplasm, with a propensity for recurrence and metastasis. Very few cases of metastases to the gastrointestinal tract have been reported in the medical literature. Objectives: The aim of this study was to report a case of MCC metastasizing to the stomach, its clinical presentation, and its management. Methods: A PubMed search was made using the following search terms: "Merkel cell carcinoma," "gastric," and "metastasis." Results: The investigators report a case of MCC metastatic to the stomach presenting with melena, syncope, early satiety, increasing fatigue, and unintentional weight loss. The other known cases of gastrointestinal metastasis of MCC are summarized and critically reviewed. Conclusions: Although MCC spreading to the stomach is exceedingly rare, because of MCC's high recurrence rate and metastatic potential, it should be considered in patients with histories of MCC presenting with recent weight loss, early satiety, and gastrointestinal bleeding.
AB - Background: Merkel cell carcinoma (MCC) is a rare, highly aggressive cutaneous neoplasm, with a propensity for recurrence and metastasis. Very few cases of metastases to the gastrointestinal tract have been reported in the medical literature. Objectives: The aim of this study was to report a case of MCC metastasizing to the stomach, its clinical presentation, and its management. Methods: A PubMed search was made using the following search terms: "Merkel cell carcinoma," "gastric," and "metastasis." Results: The investigators report a case of MCC metastatic to the stomach presenting with melena, syncope, early satiety, increasing fatigue, and unintentional weight loss. The other known cases of gastrointestinal metastasis of MCC are summarized and critically reviewed. Conclusions: Although MCC spreading to the stomach is exceedingly rare, because of MCC's high recurrence rate and metastatic potential, it should be considered in patients with histories of MCC presenting with recent weight loss, early satiety, and gastrointestinal bleeding.
KW - Gastric metastasis
KW - Merkel cell carcinoma
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U2 - 10.1177/1203475415623509
DO - 10.1177/1203475415623509
M3 - Review article
C2 - 26676953
AN - SCOPUS:84965082228
SN - 1203-4754
VL - 20
SP - 255
EP - 258
JO - Journal of cutaneous medicine and surgery
JF - Journal of cutaneous medicine and surgery
IS - 3
ER -