Metastatic Breast Cancer to the Uterus and Cervix

Background: Breast cancer can metastasize to pelvic organs, including ovaries. However, there are a limited number of reported metastases to the uterus and cervix. Case report: A 52-year-old white female with a history of invasive ductal and lobular breast carcinoma presented with an 18-month history of intermittent vaginal bleeding and pelvic pain. On cervical biopsy, she was found to have metastatic adenocarcinoma, consistent with breast cancer. Because of persistent bleeding and pelvic pain, the patient elected to undergo a palliative total abdominal hysterectomy and bilateral salpingo-oophorectomy. Pathologic examination revealed metastatic infiltrating ductal and lobular carcinoma involving the entire cervix, uterus, both tubes and ovaries. There was no evidence of disease elsewhere. The serosa did not show any involvement of cancer. The postoperative course was uncomplicated, and she achieved palliation of her symptoms. Sixteen months after her surgery, however, the patient succumbed to recurrent breast cancer and died. Conclusion: Metastatic breast cancer to the uterus and cervix is relatively uncommon. Selected patients may benefit from palliative surgery.