Metastatic uterine papillary serous carcinoma to the pericardium

Pedro T. Ramirez; Lois M. Ramondetta; Thomas W. Burke; David M. Gershenson; Molly A. Brewer

doi:10.1006/gyno.2001.6351

Metastatic uterine papillary serous carcinoma to the pericardium

Pedro T. Ramirez, Lois M. Ramondetta, Thomas W. Burke, David M. Gershenson, Molly A. Brewer

Gynecological Oncology & Reproductive Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Background. Uterine papillary serous carcinoma is an aggressive tumor with a high propensity for distant spread. Metastases to the heart or pericardium are rare in gynecologic malignancies and usually fatal. Case. A 64-year-old African American woman was diagnosed with recurrent uterine papillary serous carcinoma metastatic to the pericardium. Her case at presentation was significant for an elevated serum CA-125, evidence of metastatic disease to the liver, and massive cardiomegaly. Cytologic analysis of fluid obtained by pericardiocentesis confirmed recurrence. Despite treatment with paclitaxel and a pleuropericardial window, the patient succumbed to her disease. Conclusion. The prognosis for patients whose recurrent uterine papillary serous carcinoma has metastasized to the heart or pericardium is extremely poor. Effective adjuvant and salvage therapies are essential.

Original language	English (US)
Pages (from-to)	135-137
Number of pages	3
Journal	Gynecologic oncology
Volume	83
Issue number	1
DOIs	https://doi.org/10.1006/gyno.2001.6351
State	Published - 2001

Keywords

Papillary serous adenocarcinoma
Pericardial metastasis
Uterine cancer

ASJC Scopus subject areas

Oncology
Obstetrics and Gynecology

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10.1006/gyno.2001.6351

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title = "Metastatic uterine papillary serous carcinoma to the pericardium",

abstract = "Background. Uterine papillary serous carcinoma is an aggressive tumor with a high propensity for distant spread. Metastases to the heart or pericardium are rare in gynecologic malignancies and usually fatal. Case. A 64-year-old African American woman was diagnosed with recurrent uterine papillary serous carcinoma metastatic to the pericardium. Her case at presentation was significant for an elevated serum CA-125, evidence of metastatic disease to the liver, and massive cardiomegaly. Cytologic analysis of fluid obtained by pericardiocentesis confirmed recurrence. Despite treatment with paclitaxel and a pleuropericardial window, the patient succumbed to her disease. Conclusion. The prognosis for patients whose recurrent uterine papillary serous carcinoma has metastasized to the heart or pericardium is extremely poor. Effective adjuvant and salvage therapies are essential.",

keywords = "Papillary serous adenocarcinoma, Pericardial metastasis, Uterine cancer",

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T1 - Metastatic uterine papillary serous carcinoma to the pericardium

AU - Ramirez, Pedro T.

AU - Ramondetta, Lois M.

AU - Burke, Thomas W.

AU - Gershenson, David M.

AU - Brewer, Molly A.

PY - 2001

Y1 - 2001

N2 - Background. Uterine papillary serous carcinoma is an aggressive tumor with a high propensity for distant spread. Metastases to the heart or pericardium are rare in gynecologic malignancies and usually fatal. Case. A 64-year-old African American woman was diagnosed with recurrent uterine papillary serous carcinoma metastatic to the pericardium. Her case at presentation was significant for an elevated serum CA-125, evidence of metastatic disease to the liver, and massive cardiomegaly. Cytologic analysis of fluid obtained by pericardiocentesis confirmed recurrence. Despite treatment with paclitaxel and a pleuropericardial window, the patient succumbed to her disease. Conclusion. The prognosis for patients whose recurrent uterine papillary serous carcinoma has metastasized to the heart or pericardium is extremely poor. Effective adjuvant and salvage therapies are essential.

AB - Background. Uterine papillary serous carcinoma is an aggressive tumor with a high propensity for distant spread. Metastases to the heart or pericardium are rare in gynecologic malignancies and usually fatal. Case. A 64-year-old African American woman was diagnosed with recurrent uterine papillary serous carcinoma metastatic to the pericardium. Her case at presentation was significant for an elevated serum CA-125, evidence of metastatic disease to the liver, and massive cardiomegaly. Cytologic analysis of fluid obtained by pericardiocentesis confirmed recurrence. Despite treatment with paclitaxel and a pleuropericardial window, the patient succumbed to her disease. Conclusion. The prognosis for patients whose recurrent uterine papillary serous carcinoma has metastasized to the heart or pericardium is extremely poor. Effective adjuvant and salvage therapies are essential.

KW - Papillary serous adenocarcinoma

KW - Pericardial metastasis

KW - Uterine cancer

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Metastatic uterine papillary serous carcinoma to the pericardium

Abstract

Keywords

ASJC Scopus subject areas

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