Microcalcification detectability for four mammographic detectors: Flat-panel, CCD, CR, and screen/film

Xiujiang J. Rong; Chris C. Shaw; Dennis A. Johnston; Michael R. Lemacks; Xinming Liu; Gary J. Whitman; Mark J. Dryden; Tanya W. Stephens; Stephen K. Thompson; Kerry T. Krugh; Chao Jen Lai

doi:10.1118/1.1500768

Microcalcification detectability for four mammographic detectors: Flat-panel, CCD, CR, and screen/film

Xiujiang J. Rong, Chris C. Shaw, Dennis A. Johnston, Michael R. Lemacks, Xinming Liu, Gary J. Whitman, Mark J. Dryden, Tanya W. Stephens, Stephen K. Thompson, Kerry T. Krugh, Chao Jen Lai

Imaging Physics

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

Amorphous silicon/cesium iodide (a-Si:H/CsI:Tl) flat-panel (FP)-based full-field digital mammography systems have recently become commercially available for clinical use. Some investigations on physical properties and imaging characteristics of these types of detectors have been conducted and reported. In this perception study, a phantom containing simulated microcalcifications (μCs) of various sizes was imaged with four detector systems: a FP system, a small field-of-view charge coupled device (CCD) system, a high resolution computed radiography (CR) system, and a conventional mammography screen/film (SF) system. The images were reviewed by mammographers as well as nonradiologist participants. Scores reflecting confidence ratings were given and recorded for each detection task. The results were used to determine the average confidence-rating scores for the four imaging systems. Receiver operating characteristics (ROC) analysis was also performed to evaluate and compare the overall detection accuracy for the four detector systems. For calcifications of 125-140 μm in size, the FP system was found to have the best performance with the highest confidence-rating scores and the greatest detection accuracy (A_z = 0.9) in the ROC analysis. The SF system was ranked second while the CCD system outperformed the CR system. The p values obtained by applying a Student t-test to the results of the ROC analysis indicate that the differences between any two systems are statistically significant (p<0.005). Differences in μC detectability for the large (150-160 μm) and small (112-125 μm) size μC groups showed a wider range of p values (not all p values are smaller than 0.005, ranging from 0.6 to <0.001) compared to the p values obtained for the medium (125-140 μm) size μC group. Using the p values to assess the statistical significance, the use of the average confidence-rating scores was not as significant as the use of the ROC analysis p value for p value.

Original language	English (US)
Pages (from-to)	2052-2061
Number of pages	10
Journal	Medical physics
Volume	29
Issue number	9
DOIs	https://doi.org/10.1118/1.1500768
State	Published - Sep 2002

Keywords

Charge coupled device
Computed radiography
Flat-panel
Mammography
Microcalcification phantom
Screen/film

ASJC Scopus subject areas

Biophysics
Radiology Nuclear Medicine and imaging

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10.1118/1.1500768

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title = "Microcalcification detectability for four mammographic detectors: Flat-panel, CCD, CR, and screen/film",

abstract = "Amorphous silicon/cesium iodide (a-Si:H/CsI:Tl) flat-panel (FP)-based full-field digital mammography systems have recently become commercially available for clinical use. Some investigations on physical properties and imaging characteristics of these types of detectors have been conducted and reported. In this perception study, a phantom containing simulated microcalcifications (μCs) of various sizes was imaged with four detector systems: a FP system, a small field-of-view charge coupled device (CCD) system, a high resolution computed radiography (CR) system, and a conventional mammography screen/film (SF) system. The images were reviewed by mammographers as well as nonradiologist participants. Scores reflecting confidence ratings were given and recorded for each detection task. The results were used to determine the average confidence-rating scores for the four imaging systems. Receiver operating characteristics (ROC) analysis was also performed to evaluate and compare the overall detection accuracy for the four detector systems. For calcifications of 125-140 μm in size, the FP system was found to have the best performance with the highest confidence-rating scores and the greatest detection accuracy (Az = 0.9) in the ROC analysis. The SF system was ranked second while the CCD system outperformed the CR system. The p values obtained by applying a Student t-test to the results of the ROC analysis indicate that the differences between any two systems are statistically significant (p<0.005). Differences in μC detectability for the large (150-160 μm) and small (112-125 μm) size μC groups showed a wider range of p values (not all p values are smaller than 0.005, ranging from 0.6 to <0.001) compared to the p values obtained for the medium (125-140 μm) size μC group. Using the p values to assess the statistical significance, the use of the average confidence-rating scores was not as significant as the use of the ROC analysis p value for p value.",

keywords = "Charge coupled device, Computed radiography, Flat-panel, Mammography, Microcalcification phantom, Screen/film",

author = "Rong, {Xiujiang J.} and Shaw, {Chris C.} and Johnston, {Dennis A.} and Lemacks, {Michael R.} and Xinming Liu and Whitman, {Gary J.} and Dryden, {Mark J.} and Stephens, {Tanya W.} and Thompson, {Stephen K.} and Krugh, {Kerry T.} and Lai, {Chao Jen}",

year = "2002",

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doi = "10.1118/1.1500768",

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volume = "29",

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AU - Rong, Xiujiang J.

AU - Shaw, Chris C.

AU - Johnston, Dennis A.

AU - Lemacks, Michael R.

AU - Liu, Xinming

AU - Whitman, Gary J.

AU - Dryden, Mark J.

AU - Stephens, Tanya W.

AU - Thompson, Stephen K.

AU - Krugh, Kerry T.

AU - Lai, Chao Jen

PY - 2002/9

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N2 - Amorphous silicon/cesium iodide (a-Si:H/CsI:Tl) flat-panel (FP)-based full-field digital mammography systems have recently become commercially available for clinical use. Some investigations on physical properties and imaging characteristics of these types of detectors have been conducted and reported. In this perception study, a phantom containing simulated microcalcifications (μCs) of various sizes was imaged with four detector systems: a FP system, a small field-of-view charge coupled device (CCD) system, a high resolution computed radiography (CR) system, and a conventional mammography screen/film (SF) system. The images were reviewed by mammographers as well as nonradiologist participants. Scores reflecting confidence ratings were given and recorded for each detection task. The results were used to determine the average confidence-rating scores for the four imaging systems. Receiver operating characteristics (ROC) analysis was also performed to evaluate and compare the overall detection accuracy for the four detector systems. For calcifications of 125-140 μm in size, the FP system was found to have the best performance with the highest confidence-rating scores and the greatest detection accuracy (Az = 0.9) in the ROC analysis. The SF system was ranked second while the CCD system outperformed the CR system. The p values obtained by applying a Student t-test to the results of the ROC analysis indicate that the differences between any two systems are statistically significant (p<0.005). Differences in μC detectability for the large (150-160 μm) and small (112-125 μm) size μC groups showed a wider range of p values (not all p values are smaller than 0.005, ranging from 0.6 to <0.001) compared to the p values obtained for the medium (125-140 μm) size μC group. Using the p values to assess the statistical significance, the use of the average confidence-rating scores was not as significant as the use of the ROC analysis p value for p value.

AB - Amorphous silicon/cesium iodide (a-Si:H/CsI:Tl) flat-panel (FP)-based full-field digital mammography systems have recently become commercially available for clinical use. Some investigations on physical properties and imaging characteristics of these types of detectors have been conducted and reported. In this perception study, a phantom containing simulated microcalcifications (μCs) of various sizes was imaged with four detector systems: a FP system, a small field-of-view charge coupled device (CCD) system, a high resolution computed radiography (CR) system, and a conventional mammography screen/film (SF) system. The images were reviewed by mammographers as well as nonradiologist participants. Scores reflecting confidence ratings were given and recorded for each detection task. The results were used to determine the average confidence-rating scores for the four imaging systems. Receiver operating characteristics (ROC) analysis was also performed to evaluate and compare the overall detection accuracy for the four detector systems. For calcifications of 125-140 μm in size, the FP system was found to have the best performance with the highest confidence-rating scores and the greatest detection accuracy (Az = 0.9) in the ROC analysis. The SF system was ranked second while the CCD system outperformed the CR system. The p values obtained by applying a Student t-test to the results of the ROC analysis indicate that the differences between any two systems are statistically significant (p<0.005). Differences in μC detectability for the large (150-160 μm) and small (112-125 μm) size μC groups showed a wider range of p values (not all p values are smaller than 0.005, ranging from 0.6 to <0.001) compared to the p values obtained for the medium (125-140 μm) size μC group. Using the p values to assess the statistical significance, the use of the average confidence-rating scores was not as significant as the use of the ROC analysis p value for p value.

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KW - Mammography

KW - Microcalcification phantom

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Microcalcification detectability for four mammographic detectors: Flat-panel, CCD, CR, and screen/film

Abstract

Keywords

ASJC Scopus subject areas

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