Micromanaging the classification of colon cancer: The role of the microRNAome

Eduardo Vilar; Josep Tabernero; Stephen B. Gruber

doi:10.1158/1078-0432.CCR-11-2440

Micromanaging the classification of colon cancer: The role of the microRNAome

Eduardo Vilar, Josep Tabernero, Stephen B. Gruber

Research output: Contribution to journal › Comment/debate › peer-review

10 Scopus citations

Abstract

Recent advances in our understanding of the microRNAome (miRNAome) have provided further insights into the molecular pathogenesis of colorectal cancer and shown a potential role for miRNAs in distinguishing molecular subtypes. The mucosa-adenoma-carcinoma model can now integrate miRNAs into the known genetic alterations that drive the progression of colorectal neoplasia.

Original language	English (US)
Pages (from-to)	7207-7209
Number of pages	3
Journal	Clinical Cancer Research
Volume	17
Issue number	23
DOIs	https://doi.org/10.1158/1078-0432.CCR-11-2440
State	Published - Dec 1 2011
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1158/1078-0432.CCR-11-2440

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abstract = "Recent advances in our understanding of the microRNAome (miRNAome) have provided further insights into the molecular pathogenesis of colorectal cancer and shown a potential role for miRNAs in distinguishing molecular subtypes. The mucosa-adenoma-carcinoma model can now integrate miRNAs into the known genetic alterations that drive the progression of colorectal neoplasia.",

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AU - Gruber, Stephen B.

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AB - Recent advances in our understanding of the microRNAome (miRNAome) have provided further insights into the molecular pathogenesis of colorectal cancer and shown a potential role for miRNAs in distinguishing molecular subtypes. The mucosa-adenoma-carcinoma model can now integrate miRNAs into the known genetic alterations that drive the progression of colorectal neoplasia.

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Micromanaging the classification of colon cancer: The role of the microRNAome

Abstract

ASJC Scopus subject areas

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