@article{c90590e53e254da4aea9d144f21b9455,
title = "MicroRNAs miR-221 and miR-222: A new level of regulation in aggressive breast cancer",
abstract = "MicroRNAs (miRNAs) are crucial in the initiation and progression of tumors. A recent study has reported that the miRNAs miR-221 and miR-222 are involved in the promotion of an aggressive basal-like phenotype in breast cancer, functioning downstream of the RAS pathway and triggering epithelial-to-mesenchymal transition. These new insights into the roles of miR-221/222 in breast cancer metastasis, drug resistance and RAS pathways could potentially have applications in medical practice.",
author = "Shah, {Maitri Y.} and Calin, {George A.}",
note = "Funding Information: GAC is supported as a Fellow at The University of Texas MD Anderson Research Trust, and as a Fellow of the University of Texas System Regents Research Scholars program. Work in GAC{\textquoteright}s laboratory is supported in part by NIH grant 1R01CA135444, by a DOD Breast Cancer Idea Award, by Developmental Research Awards in Breast Cancer, Ovarian Cancer and Leukemia SPOREs, by a CLL Global Research Foundation grant, by a US/European Alliance for Therapy of CLL grant and by a 2009 Seena Magowitz - Pancreatic Cancer Action Network - AACR Pilot grant. We would like to thank Sunita Patterson (Department of Scientific Publications, MD Anderson Cancer Center) for her help with the editing of this article.",
year = "2011",
month = aug,
day = "31",
doi = "10.1186/gm272",
language = "English (US)",
volume = "3",
journal = "Genome medicine",
issn = "1756-994X",
publisher = "BioMed Central",
number = "8",
}