Minocycline-ethylenediaminetetraacetate lock solution for the prevention of implantable port infections in children with cancer

Ioannis Chatzinikolaou, Theodore F. Zipf, Hend Hanna, Jan Umphrey, W. Mark Roberts, Robert Sherertz, Ray Hachem, Issam Raad

Research output: Contribution to journalArticlepeer-review

79 Scopus citations

Abstract

In this prospective cohort study, minocycline-ethylenediaminetetraacetate (M-EDTA) was used as a lock solution in indwelling ports inserted in 14 children with cancer. No port infections, thrombotic events, or other adverse events were observed, compared with 10 port infections that occurred in 48 control patients whose ports were flushed with heparin. M-EDTA is a promising lock solution in long-term catheters.

Original languageEnglish (US)
Pages (from-to)116-119
Number of pages4
JournalClinical Infectious Diseases
Volume36
Issue number1
DOIs
StatePublished - Jan 1 2003

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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