MiR-sensing chemotherapy resistance in CLL

George A. Calin

doi:10.1182/blood-2008-11-189795

MiR-sensing chemotherapy resistance in CLL

George A. Calin

Graduate School of Biomedical Sciences

Research output: Contribution to journal › Comment/debate › peer-review

4 Scopus citations

Abstract

Resistance to chemotherapy is an unsolved medical problem and no clear solutions have been identified despite decades of research. In this issue of Blood, Zenz and colleagues identify miR-34a as a component of the chemotherapy resistance network inCLL. This is a remarkable finding with possible diagnostic and therapeutic consequences.

Original language	English (US)
Pages (from-to)	3652-3653
Number of pages	2
Journal	Blood
Volume	113
Issue number	16
DOIs	https://doi.org/10.1182/blood-2008-11-189795
State	Published - 2009

ASJC Scopus subject areas

Biochemistry
Immunology
Hematology
Cell Biology

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10.1182/blood-2008-11-189795

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title = "MiR-sensing chemotherapy resistance in CLL",

abstract = "Resistance to chemotherapy is an unsolved medical problem and no clear solutions have been identified despite decades of research. In this issue of Blood, Zenz and colleagues identify miR-34a as a component of the chemotherapy resistance network inCLL. This is a remarkable finding with possible diagnostic and therapeutic consequences.",

author = "Calin, {George A.}",

note = "Funding Information: This work was supported by National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases grants R24 DK099808 and R01 DK087992, and a Bridge Grant from the American Society of Hematology.",

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doi = "10.1182/blood-2008-11-189795",

language = "English (US)",

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publisher = "American Society of Hematology",

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T1 - MiR-sensing chemotherapy resistance in CLL

AU - Calin, George A.

N1 - Funding Information: This work was supported by National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases grants R24 DK099808 and R01 DK087992, and a Bridge Grant from the American Society of Hematology.

PY - 2009

Y1 - 2009

N2 - Resistance to chemotherapy is an unsolved medical problem and no clear solutions have been identified despite decades of research. In this issue of Blood, Zenz and colleagues identify miR-34a as a component of the chemotherapy resistance network inCLL. This is a remarkable finding with possible diagnostic and therapeutic consequences.

AB - Resistance to chemotherapy is an unsolved medical problem and no clear solutions have been identified despite decades of research. In this issue of Blood, Zenz and colleagues identify miR-34a as a component of the chemotherapy resistance network inCLL. This is a remarkable finding with possible diagnostic and therapeutic consequences.

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DO - 10.1182/blood-2008-11-189795

M3 - Comment/debate

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JO - Blood

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ER -

MiR-sensing chemotherapy resistance in CLL

Abstract

ASJC Scopus subject areas

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