MiRly regulating metabolism

Deepa Sampath

doi:10.1182/blood-2012-08-439596

MiRly regulating metabolism

Deepa Sampath

Hematopoietic Biology & Malignancy

Research output: Contribution to journal › Comment/debate › peer-review

2 Scopus citations

Abstract

In this issue of Blood, Tili et al identify an important link between microRNAs and,themetabolic adaptation characteristic of cancer cells.1 In chronic lymphocytic leukemia (CLL), the microRNA, miR-125b becomes down-regulated resulting in an increase in the expression and activity of amyriad of metabolic enzymes that promote metabolic reprogramming in a way that favors malignant transformation.

Original language	English (US)
Pages (from-to)	2540-2541
Number of pages	2
Journal	Blood
Volume	120
Issue number	13
DOIs	https://doi.org/10.1182/blood-2012-08-439596
State	Published - Sep 27 2012

ASJC Scopus subject areas

Biochemistry
Immunology
Hematology
Cell Biology

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10.1182/blood-2012-08-439596

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title = "MiRly regulating metabolism",

abstract = "In this issue of Blood, Tili et al identify an important link between microRNAs and,themetabolic adaptation characteristic of cancer cells.1 In chronic lymphocytic leukemia (CLL), the microRNA, miR-125b becomes down-regulated resulting in an increase in the expression and activity of amyriad of metabolic enzymes that promote metabolic reprogramming in a way that favors malignant transformation.",

author = "Deepa Sampath",

year = "2012",

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doi = "10.1182/blood-2012-08-439596",

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AU - Sampath, Deepa

PY - 2012/9/27

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N2 - In this issue of Blood, Tili et al identify an important link between microRNAs and,themetabolic adaptation characteristic of cancer cells.1 In chronic lymphocytic leukemia (CLL), the microRNA, miR-125b becomes down-regulated resulting in an increase in the expression and activity of amyriad of metabolic enzymes that promote metabolic reprogramming in a way that favors malignant transformation.

AB - In this issue of Blood, Tili et al identify an important link between microRNAs and,themetabolic adaptation characteristic of cancer cells.1 In chronic lymphocytic leukemia (CLL), the microRNA, miR-125b becomes down-regulated resulting in an increase in the expression and activity of amyriad of metabolic enzymes that promote metabolic reprogramming in a way that favors malignant transformation.

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DO - 10.1182/blood-2012-08-439596

M3 - Comment/debate

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SN - 0006-4971

VL - 120

SP - 2540

EP - 2541

JO - Blood

JF - Blood

IS - 13

ER -

MiRly regulating metabolism

Abstract

ASJC Scopus subject areas

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