Abstract
A 65-year-old man with fluciclovine-avid metastatic prostate small cell carcinoma with prostate-specific antigen (PSA) 19.4 ng/mL at diagnosis underwent system therapy and subsequent surgery and achieved hormonal response with PSA <0.1 ng/mL. An 18F-fluciclovine PET/CT scan 3 months after surgery was negative for disease. Although PSA remained <0.1 ng/mL, the rising carcinoembryonic antigen prompted an 18F-FDG PET/CT 6 weeks later. It showed multiple hypermetabolic lesions in the prostatectomy bed, liver, and right iliac bone, suggestive of malignant disease. The FDG-avid prostatectomy lesions were further confirmed on MRI. This case demonstrates that FDG PET/CT has a role in suspected metastatic prostate small cell carcinoma with negative fluciclovine PET examination.
Original language | English (US) |
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Pages (from-to) | 255-257 |
Number of pages | 3 |
Journal | Clinical nuclear medicine |
Volume | 47 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1 2022 |
Keywords
- FDG
- PET/CT
- fluciclovine
- metastasis
- prostate small cell carcinoma
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging