Models of inflammatory breast cancer

Lara Lacerda; Wendy A. Woodward

doi:10.1007/978-94-007-3907-9_13

Models of inflammatory breast cancer

Lara Lacerda, Wendy A. Woodward

Radiation Oncology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

4 Scopus citations

Abstract

Inflammatory Breast Cancer (IBC) is a rare and difficult to characterize subtype of breast cancer for which few in vitro and in vivo models are currently available. In this chapter we describe the characteristics and limitations of the models that have been published to further study the pathology of IBC and to develop therapeutic approaches for IBC. Published information regarding receptor status, E—cadherin expression, 2D and 3D culture, xenografts, ability to form metastases and identified tumor-initiation cell sub-populations are reviewed.

Original language	English (US)
Title of host publication	Inflammatory Breast Cancer
Subtitle of host publication	An Update
Publisher	Springer Netherlands
Pages	139-150
Number of pages	12
ISBN (Electronic)	9789400739079
ISBN (Print)	9789400739062
DOIs	https://doi.org/10.1007/978-94-007-3907-9_13
State	Published - Jan 1 2012

Keywords

Animal models
Inflammatory breast cancer
KLP4
MDA-IBC-3
Mary-X
SUM149
SUM190
WIBC-9
Xenografts

ASJC Scopus subject areas

General Medicine

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10.1007/978-94-007-3907-9_13

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abstract = "Inflammatory Breast Cancer (IBC) is a rare and difficult to characterize subtype of breast cancer for which few in vitro and in vivo models are currently available. In this chapter we describe the characteristics and limitations of the models that have been published to further study the pathology of IBC and to develop therapeutic approaches for IBC. Published information regarding receptor status, E—cadherin expression, 2D and 3D culture, xenografts, ability to form metastases and identified tumor-initiation cell sub-populations are reviewed.",

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N2 - Inflammatory Breast Cancer (IBC) is a rare and difficult to characterize subtype of breast cancer for which few in vitro and in vivo models are currently available. In this chapter we describe the characteristics and limitations of the models that have been published to further study the pathology of IBC and to develop therapeutic approaches for IBC. Published information regarding receptor status, E—cadherin expression, 2D and 3D culture, xenografts, ability to form metastases and identified tumor-initiation cell sub-populations are reviewed.

AB - Inflammatory Breast Cancer (IBC) is a rare and difficult to characterize subtype of breast cancer for which few in vitro and in vivo models are currently available. In this chapter we describe the characteristics and limitations of the models that have been published to further study the pathology of IBC and to develop therapeutic approaches for IBC. Published information regarding receptor status, E—cadherin expression, 2D and 3D culture, xenografts, ability to form metastases and identified tumor-initiation cell sub-populations are reviewed.

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KW - MDA-IBC-3

KW - Mary-X

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KW - SUM190

KW - WIBC-9

KW - Xenografts

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BT - Inflammatory Breast Cancer

PB - Springer Netherlands

ER -

Models of inflammatory breast cancer

Abstract

Keywords

ASJC Scopus subject areas

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