Molecular cloning and expression analysis of a novel human cDNA fragment encoding a putative Ser/Thr protein kinase

Qi Zhang; Fangyan Dai; Min Zhang; Peirong Hu; Qiang Fu; Yuxin Fan; Long Yu; Shouyuan Zhao

doi:10.1007/BF02885018

Molecular cloning and expression analysis of a novel human cDNA fragment encoding a putative Ser/Thr protein kinase

Qi Zhang, Fangyan Dai, Min Zhang, Peirong Hu, Qiang Fu, Yuxin Fan, Long Yu, Shouyuan Zhao

Experimental Radiation Oncology

Research output: Contribution to journal › Article › peer-review

Abstract

A novel full-length cDNA encoding a putative serine/threonine kinase has been isolated from a human testis cDNA library. A nucleotide sequence of 1225 bp length has been determined containing an open reading frame of 1 044 nucleotides (encoding 348 amino acids). In view of its degree of homology to members of the Ser/Thr protein kinase family and the closest relationship to Mus musculus STK-1, the predicted product was designated by the name of HUMSTK-1. Its mRNA is present in large amounts in thymus, and small amounts in testis, small intestine and colon.

Original language	English (US)
Pages (from-to)	778-783
Number of pages	6
Journal	Chinese Science Bulletin
Volume	44
Issue number	9
DOIs	https://doi.org/10.1007/BF02885018
State	Published - May 1999

Keywords

Cell cycle
Homology
Serine/threonine kinase
cDNA

ASJC Scopus subject areas

General

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10.1007/BF02885018

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title = "Molecular cloning and expression analysis of a novel human cDNA fragment encoding a putative Ser/Thr protein kinase",

abstract = "A novel full-length cDNA encoding a putative serine/threonine kinase has been isolated from a human testis cDNA library. A nucleotide sequence of 1225 bp length has been determined containing an open reading frame of 1 044 nucleotides (encoding 348 amino acids). In view of its degree of homology to members of the Ser/Thr protein kinase family and the closest relationship to Mus musculus STK-1, the predicted product was designated by the name of HUMSTK-1. Its mRNA is present in large amounts in thymus, and small amounts in testis, small intestine and colon.",

keywords = "Cell cycle, Homology, Serine/threonine kinase, cDNA",

author = "Qi Zhang and Fangyan Dai and Min Zhang and Peirong Hu and Qiang Fu and Yuxin Fan and Long Yu and Shouyuan Zhao",

note = "Funding Information: Acknowledgement The authors are grateful to Deming Su for critical reading of the manuscript. This work was supported by the Ka-tional Outstanding Young Scientist Foundation of China (Grant No. 39525015), the National Natural Science Foundation of China (Grant No. 3%80019). the State {"}863{"} lligh-Tech Program (Grant No. 863-%19020401) and Shanghai life Science Center.",

year = "1999",

month = may,

doi = "10.1007/BF02885018",

language = "English (US)",

volume = "44",

pages = "778--783",

journal = "Chinese Science Bulletin",

issn = "1001-6538",

publisher = "Springer Science + Business Media",

number = "9",

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TY - JOUR

T1 - Molecular cloning and expression analysis of a novel human cDNA fragment encoding a putative Ser/Thr protein kinase

AU - Zhang, Qi

AU - Dai, Fangyan

AU - Zhang, Min

AU - Hu, Peirong

AU - Fu, Qiang

AU - Fan, Yuxin

AU - Yu, Long

AU - Zhao, Shouyuan

N1 - Funding Information: Acknowledgement The authors are grateful to Deming Su for critical reading of the manuscript. This work was supported by the Ka-tional Outstanding Young Scientist Foundation of China (Grant No. 39525015), the National Natural Science Foundation of China (Grant No. 3%80019). the State "863" lligh-Tech Program (Grant No. 863-%19020401) and Shanghai life Science Center.

PY - 1999/5

Y1 - 1999/5

N2 - A novel full-length cDNA encoding a putative serine/threonine kinase has been isolated from a human testis cDNA library. A nucleotide sequence of 1225 bp length has been determined containing an open reading frame of 1 044 nucleotides (encoding 348 amino acids). In view of its degree of homology to members of the Ser/Thr protein kinase family and the closest relationship to Mus musculus STK-1, the predicted product was designated by the name of HUMSTK-1. Its mRNA is present in large amounts in thymus, and small amounts in testis, small intestine and colon.

AB - A novel full-length cDNA encoding a putative serine/threonine kinase has been isolated from a human testis cDNA library. A nucleotide sequence of 1225 bp length has been determined containing an open reading frame of 1 044 nucleotides (encoding 348 amino acids). In view of its degree of homology to members of the Ser/Thr protein kinase family and the closest relationship to Mus musculus STK-1, the predicted product was designated by the name of HUMSTK-1. Its mRNA is present in large amounts in thymus, and small amounts in testis, small intestine and colon.

KW - Cell cycle

KW - Homology

KW - Serine/threonine kinase

KW - cDNA

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DO - 10.1007/BF02885018

M3 - Article

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SN - 1001-6538

VL - 44

SP - 778

EP - 783

JO - Chinese Science Bulletin

JF - Chinese Science Bulletin

IS - 9

ER -

Molecular cloning and expression analysis of a novel human cDNA fragment encoding a putative Ser/Thr protein kinase

Abstract

Keywords

ASJC Scopus subject areas

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