Abstract
In this paper, we bring together the advances of in vivo optical imaging and modern nano-chemistry to permit optical imaging with molecular specificity. We present optically interrogated contrast agents based on metal nanocrystals attached to probe molecules with a high affinity to a specific biomarker on the surface of epithelial cancer cells. We demonstrated that unique optical properties of metal nanoparticles can be used to develop novel optically-interrogatable contrast agents for confocal reflectance imaging of pre-cancers.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2327-2328 |
| Number of pages | 2 |
| Journal | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
| Volume | 3 |
| State | Published - 2002 |
| Event | Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States Duration: Oct 23 2002 → Oct 26 2002 |
Keywords
- Cancer imaging
- Contrast agents
- Gold nanoparticles
ASJC Scopus subject areas
- Signal Processing
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Health Informatics