Molecular therapeutic agents for noninvasive photoacoustic image-guided photothermal therapy.

Pratixa P. Joshi; Yun Sheng Chen; Seungsoo Kim; Jignesh Shah; Konstantin Sokolov; Stanislav Emelianov

Molecular therapeutic agents for noninvasive photoacoustic image-guided photothermal therapy.

Pratixa P. Joshi, Yun Sheng Chen, Seungsoo Kim, Jignesh Shah, Konstantin Sokolov, Stanislav Emelianov

Research output: Contribution to journal › Article › peer-review

Abstract

Gold nanoparticles are attracting increasing attention in nanomedicine due to their inherently low toxicity and unique optical properties. In particular, gold nanorods have been used in the thermal therapy due to their tunable strong longitudinal plasmon resonance in the near infra-red region and high conversion efficiency from optical to thermal energy. In this study we explore the potential of gold nanorods for photoacoustic image-guided photothermal therapy to treat cancers. We synthesize the gold nanorods and make them biocompatible by replacing the cytotoxic surfactant used in the synthesis (cetyl trimethyl ammonium bromide) with a biocompatible molecule and then demonstrate the targeting to the cancer cells by bioconjugation of the modified nanorods.

Original language	English (US)
Pages (from-to)	4106-4109
Number of pages	4
Journal	Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
State	Published - 2009

ASJC Scopus subject areas

Computer Vision and Pattern Recognition
Signal Processing
Biomedical Engineering
Health Informatics

Cite this

Molecular therapeutic agents for noninvasive photoacoustic image-guided photothermal therapy. / Joshi, Pratixa P.; Chen, Yun Sheng; Kim, Seungsoo et al.
In: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2009, p. 4106-4109.

Research output: Contribution to journal › Article › peer-review

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AU - Sokolov, Konstantin

AU - Emelianov, Stanislav

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Molecular therapeutic agents for noninvasive photoacoustic image-guided photothermal therapy.

Abstract

ASJC Scopus subject areas

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