Molybdenum-based hetero-nanocomposites for cancer therapy, diagnosis and biosensing application: Current advancement and future breakthroughs

Namdev Dhas; Ritu Kudarha; Atul Garkal; Vivek Ghate; Shilpa Sharma; Prabhakar Panzade; Shubham Khot; Pinal Chaudhari; Ashutosh Singh; Mitali Paryani; Shaila Lewis; Neha Garg; Narinder Singh; Priyanka Bangar; Tejal Mehta

doi:10.1016/j.jconrel.2020.12.015

Molybdenum-based hetero-nanocomposites for cancer therapy, diagnosis and biosensing application: Current advancement and future breakthroughs

Namdev Dhas, Ritu Kudarha, Atul Garkal, Vivek Ghate, Shilpa Sharma, Prabhakar Panzade, Shubham Khot, Pinal Chaudhari, Ashutosh Singh, Mitali Paryani, Shaila Lewis, Neha Garg, Narinder Singh, Priyanka Bangar, Tejal Mehta

Research output: Contribution to journal › Review article › peer-review

44 Scopus citations

Abstract

In recent years, there have been significant advancements in the nanotechnology for cancer therapy. Even though molybdenum disulphide (MoS2)-based nanocomposites demonstrated extensive applications in biosensing, bioimaging, phototherapy, the review article focusing on MoS2 nanocomposite platform has not been accounted for yet. The review summarizes recent strategies on design and fabrication of MoS2-based nanocomposites and their modulated properties in cancer treatment. The review also discussed several therapeutic strategies (photothermal, photodynamic, immunotherapy, gene therapy and chemotherapy) and their combinations for efficient cancer therapy along with certain case studies. The review also inculcates various diagnostic techniques viz. magnetic resonance imaging, computed tomography, photoacoustic imaging and fluorescence imaging for diagnosis of cancer.

Original language	English (US)
Pages (from-to)	257-283
Number of pages	27
Journal	Journal of Controlled Release
Volume	330
DOIs	https://doi.org/10.1016/j.jconrel.2020.12.015
State	Published - Feb 10 2021
Externally published	Yes

Keywords

Biomedical applications
Chemotherapy
Magnetic resonance imaging
Molybdenum disulphide
Photoacoustic imaging
Phototherapy

ASJC Scopus subject areas

Pharmaceutical Science

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10.1016/j.jconrel.2020.12.015

Cite this

Dhas, N., Kudarha, R., Garkal, A., Ghate, V., Sharma, S., Panzade, P., Khot, S., Chaudhari, P., Singh, A., Paryani, M., Lewis, S., Garg, N., Singh, N., Bangar, P., & Mehta, T. (2021). Molybdenum-based hetero-nanocomposites for cancer therapy, diagnosis and biosensing application: Current advancement and future breakthroughs. Journal of Controlled Release, 330, 257-283. https://doi.org/10.1016/j.jconrel.2020.12.015

Dhas, N, Kudarha, R, Garkal, A, Ghate, V, Sharma, S, Panzade, P, Khot, S, Chaudhari, P, Singh, A, Paryani, M, Lewis, S, Garg, N, Singh, N, Bangar, P & Mehta, T 2021, 'Molybdenum-based hetero-nanocomposites for cancer therapy, diagnosis and biosensing application: Current advancement and future breakthroughs', Journal of Controlled Release, vol. 330, pp. 257-283. https://doi.org/10.1016/j.jconrel.2020.12.015

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abstract = "In recent years, there have been significant advancements in the nanotechnology for cancer therapy. Even though molybdenum disulphide (MoS2)-based nanocomposites demonstrated extensive applications in biosensing, bioimaging, phototherapy, the review article focusing on MoS2 nanocomposite platform has not been accounted for yet. The review summarizes recent strategies on design and fabrication of MoS2-based nanocomposites and their modulated properties in cancer treatment. The review also discussed several therapeutic strategies (photothermal, photodynamic, immunotherapy, gene therapy and chemotherapy) and their combinations for efficient cancer therapy along with certain case studies. The review also inculcates various diagnostic techniques viz. magnetic resonance imaging, computed tomography, photoacoustic imaging and fluorescence imaging for diagnosis of cancer.",

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AU - Ghate, Vivek

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AU - Panzade, Prabhakar

AU - Khot, Shubham

AU - Chaudhari, Pinal

AU - Singh, Ashutosh

AU - Paryani, Mitali

AU - Lewis, Shaila

AU - Garg, Neha

AU - Singh, Narinder

AU - Bangar, Priyanka

AU - Mehta, Tejal

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AB - In recent years, there have been significant advancements in the nanotechnology for cancer therapy. Even though molybdenum disulphide (MoS2)-based nanocomposites demonstrated extensive applications in biosensing, bioimaging, phototherapy, the review article focusing on MoS2 nanocomposite platform has not been accounted for yet. The review summarizes recent strategies on design and fabrication of MoS2-based nanocomposites and their modulated properties in cancer treatment. The review also discussed several therapeutic strategies (photothermal, photodynamic, immunotherapy, gene therapy and chemotherapy) and their combinations for efficient cancer therapy along with certain case studies. The review also inculcates various diagnostic techniques viz. magnetic resonance imaging, computed tomography, photoacoustic imaging and fluorescence imaging for diagnosis of cancer.

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KW - Magnetic resonance imaging

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Molybdenum-based hetero-nanocomposites for cancer therapy, diagnosis and biosensing application: Current advancement and future breakthroughs

Abstract

Keywords

ASJC Scopus subject areas

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