Monte carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET

Shitao Liu; Jiguo Liu; Yuxuan Zhang; Hongdi Li; Rocio Ramirez; Hossain Baghaei; Shaohui An; Chao Wang; Wai Hoi Wong

doi:10.1109/NSSMIC.2008.4774421

Monte carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET

Shitao Liu, Jiguo Liu, Yuxuan Zhang, Hongdi Li, Rocio Ramirez, Hossain Baghaei, Shaohui An, Chao Wang, Wai Hoi Wong

Cancer Systems Imaging

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

We developed a detailed Monte Carlo simulation method to study the time resolution of detector for time-of-flight positron emission tomography (TOF PET). The process of gamma ray reaction in detector, scintillation light emission and transport inside the detector, the photoelectron generation and anode signal generation in the photomultiplier tube (PMT), and the electronics process of discriminator are simulated. We tested this simulation method using published experimental data, and found that it can generate reliable results. Using this method, we simulated the time resolution for a 13x13 detector block of 4x4x20 mm³ lutetium orthosilicate (LSO) crystals coupled to four 2-inch PMTs using PMT-quadrant-sharing (PQS) technology. We analyzed the effects of several factors, including the numberof hotoelectrons, light transport, transit time spread (TTS), and the depth of interaction The simulation results indicated that system time resolution of 300-350ps should be possible with currently available fast PM . This simulation method can also be used to simulate the time resolution of other detector design method.

Original language	English (US)
Title of host publication	2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
Pages	4622-4628
Number of pages	7
DOIs	https://doi.org/10.1109/NSSMIC.2008.4774421
State	Published - 2008
Event	2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008 - Dresden, Germany Duration: Oct 19 2008 → Oct 25 2008

Publication series

Name	IEEE Nuclear Science Symposium Conference Record
ISSN (Print)	1095-7863

Other

Other	2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
Country/Territory	Germany
City	Dresden
Period	10/19/08 → 10/25/08

Keywords

L(Y)SO detector block
Monte Carlo simulation
Time-of-flight PET

ASJC Scopus subject areas

Radiation
Nuclear and High Energy Physics
Radiology Nuclear Medicine and imaging

Access to Document

10.1109/NSSMIC.2008.4774421

Cite this

Liu, S., Liu, J., Zhang, Y., Li, H., Ramirez, R., Baghaei, H., An, S., Wang, C., & Wong, W. H. (2008). Monte carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET. In 2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008 (pp. 4622-4628). Article 4774421 (IEEE Nuclear Science Symposium Conference Record). https://doi.org/10.1109/NSSMIC.2008.4774421

Monte carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET. / Liu, Shitao; Liu, Jiguo; Zhang, Yuxuan et al.
2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008. 2008. p. 4622-4628 4774421 (IEEE Nuclear Science Symposium Conference Record).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Liu, S, Liu, J, Zhang, Y, Li, H, Ramirez, R, Baghaei, H, An, S, Wang, C & Wong, WH 2008, Monte carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET. in 2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008., 4774421, IEEE Nuclear Science Symposium Conference Record, pp. 4622-4628, 2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008, Dresden, Germany, 10/19/08. https://doi.org/10.1109/NSSMIC.2008.4774421

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title = "Monte carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET",

abstract = "We developed a detailed Monte Carlo simulation method to study the time resolution of detector for time-of-flight positron emission tomography (TOF PET). The process of gamma ray reaction in detector, scintillation light emission and transport inside the detector, the photoelectron generation and anode signal generation in the photomultiplier tube (PMT), and the electronics process of discriminator are simulated. We tested this simulation method using published experimental data, and found that it can generate reliable results. Using this method, we simulated the time resolution for a 13x13 detector block of 4x4x20 mm3 lutetium orthosilicate (LSO) crystals coupled to four 2-inch PMTs using PMT-quadrant-sharing (PQS) technology. We analyzed the effects of several factors, including the numberof hotoelectrons, light transport, transit time spread (TTS), and the depth of interaction The simulation results indicated that system time resolution of 300-350ps should be possible with currently available fast PM . This simulation method can also be used to simulate the time resolution of other detector design method.",

keywords = "L(Y)SO detector block, Monte Carlo simulation, Time-of-flight PET",

author = "Shitao Liu and Jiguo Liu and Yuxuan Zhang and Hongdi Li and Rocio Ramirez and Hossain Baghaei and Shaohui An and Chao Wang and Wong, {Wai Hoi}",

year = "2008",

doi = "10.1109/NSSMIC.2008.4774421",

language = "English (US)",

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AU - Li, Hongdi

AU - Ramirez, Rocio

AU - Baghaei, Hossain

AU - An, Shaohui

AU - Wang, Chao

AU - Wong, Wai Hoi

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AB - We developed a detailed Monte Carlo simulation method to study the time resolution of detector for time-of-flight positron emission tomography (TOF PET). The process of gamma ray reaction in detector, scintillation light emission and transport inside the detector, the photoelectron generation and anode signal generation in the photomultiplier tube (PMT), and the electronics process of discriminator are simulated. We tested this simulation method using published experimental data, and found that it can generate reliable results. Using this method, we simulated the time resolution for a 13x13 detector block of 4x4x20 mm3 lutetium orthosilicate (LSO) crystals coupled to four 2-inch PMTs using PMT-quadrant-sharing (PQS) technology. We analyzed the effects of several factors, including the numberof hotoelectrons, light transport, transit time spread (TTS), and the depth of interaction The simulation results indicated that system time resolution of 300-350ps should be possible with currently available fast PM . This simulation method can also be used to simulate the time resolution of other detector design method.

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Monte carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET

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