Monte Carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET

Jiguo Liu; Shitao Liu; Hongdi Li; Soonseok Kim; Yuxuan Zhang; Hossain Baghaei; Rocio Ramirez; Wai Hoi Wong

doi:10.1109/NSSMIC.2007.4436839

Monte Carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET

Jiguo Liu, Shitao Liu, Hongdi Li, Soonseok Kim, Yuxuan Zhang, Hossain Baghaei, Rocio Ramirez, Wai Hoi Wong

Cancer Systems Imaging

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

We developed a detailed Monte Carlo simulation method to study the time resolution of time-of-flight positron emission tomography (TOF PET). The process of scintillation light emission and transport inside the detector, the photoelectron generation and anode signal generation in the photomultiplier tube (PMT), and the electronics process of discriminator are simulated. We tested this simulation method using published experimental data, and found that it can generate reliable results. Using this method, we simulated the time resolution for a 13×13 detector block of 4×4×20 mm³ lutetium orthosilicate (LSO) crystals coupled to four 2-inch PMTs using PMT-quadrant-sharing (PQS) technology. We analyzed the effects of several factors, including the number of photoelectrons, light transport, transit time spread (TTS), transit time difference between center and edge of the PMT photocathode (Δ t_C-E), and the depth of interaction (DOI). The simulation results indicated that system time resolution of 300-350ps should be possible with currently available fast PMTs. This simulation method can also be used to simulate the time resolution of other detector design method.

Original language	English (US)
Title of host publication	2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
Pages	3294-3304
Number of pages	11
DOIs	https://doi.org/10.1109/NSSMIC.2007.4436839
State	Published - 2007
Event	2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC - Honolulu, HI, United States Duration: Oct 27 2007 → Nov 3 2007

Publication series

Name	IEEE Nuclear Science Symposium Conference Record
Volume	5
ISSN (Print)	1095-7863

Other

Other	2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
Country/Territory	United States
City	Honolulu, HI
Period	10/27/07 → 11/3/07

Keywords

LSO detector block
Monte Carlo simulation
Time-of-flight PET

ASJC Scopus subject areas

Radiation
Nuclear and High Energy Physics
Radiology Nuclear Medicine and imaging

Access to Document

10.1109/NSSMIC.2007.4436839

Cite this

Liu, J., Liu, S., Li, H., Kim, S., Zhang, Y., Baghaei, H., Ramirez, R., & Wong, W. H. (2007). Monte Carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET. In 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC (pp. 3294-3304). Article 4436839 (IEEE Nuclear Science Symposium Conference Record; Vol. 5). https://doi.org/10.1109/NSSMIC.2007.4436839

Monte Carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET. / Liu, Jiguo; Liu, Shitao; Li, Hongdi et al.
2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC. 2007. p. 3294-3304 4436839 (IEEE Nuclear Science Symposium Conference Record; Vol. 5).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Liu, J, Liu, S, Li, H, Kim, S, Zhang, Y, Baghaei, H, Ramirez, R & Wong, WH 2007, Monte Carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET. in 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC., 4436839, IEEE Nuclear Science Symposium Conference Record, vol. 5, pp. 3294-3304, 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC, Honolulu, HI, United States, 10/27/07. https://doi.org/10.1109/NSSMIC.2007.4436839

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title = "Monte Carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET",

abstract = "We developed a detailed Monte Carlo simulation method to study the time resolution of time-of-flight positron emission tomography (TOF PET). The process of scintillation light emission and transport inside the detector, the photoelectron generation and anode signal generation in the photomultiplier tube (PMT), and the electronics process of discriminator are simulated. We tested this simulation method using published experimental data, and found that it can generate reliable results. Using this method, we simulated the time resolution for a 13×13 detector block of 4×4×20 mm3 lutetium orthosilicate (LSO) crystals coupled to four 2-inch PMTs using PMT-quadrant-sharing (PQS) technology. We analyzed the effects of several factors, including the number of photoelectrons, light transport, transit time spread (TTS), transit time difference between center and edge of the PMT photocathode (Δ tC-E), and the depth of interaction (DOI). The simulation results indicated that system time resolution of 300-350ps should be possible with currently available fast PMTs. This simulation method can also be used to simulate the time resolution of other detector design method.",

keywords = "LSO detector block, Monte Carlo simulation, Time-of-flight PET",

author = "Jiguo Liu and Shitao Liu and Hongdi Li and Soonseok Kim and Yuxuan Zhang and Hossain Baghaei and Rocio Ramirez and Wong, {Wai Hoi}",

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doi = "10.1109/NSSMIC.2007.4436839",

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AU - Zhang, Yuxuan

AU - Baghaei, Hossain

AU - Ramirez, Rocio

AU - Wong, Wai Hoi

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AB - We developed a detailed Monte Carlo simulation method to study the time resolution of time-of-flight positron emission tomography (TOF PET). The process of scintillation light emission and transport inside the detector, the photoelectron generation and anode signal generation in the photomultiplier tube (PMT), and the electronics process of discriminator are simulated. We tested this simulation method using published experimental data, and found that it can generate reliable results. Using this method, we simulated the time resolution for a 13×13 detector block of 4×4×20 mm3 lutetium orthosilicate (LSO) crystals coupled to four 2-inch PMTs using PMT-quadrant-sharing (PQS) technology. We analyzed the effects of several factors, including the number of photoelectrons, light transport, transit time spread (TTS), transit time difference between center and edge of the PMT photocathode (Δ tC-E), and the depth of interaction (DOI). The simulation results indicated that system time resolution of 300-350ps should be possible with currently available fast PMTs. This simulation method can also be used to simulate the time resolution of other detector design method.

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KW - Time-of-flight PET

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Monte Carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET

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Keywords

ASJC Scopus subject areas

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