Mood disorders and immunity

Adam Keith Walker, Robert Dantzer, Keith W. Kelley

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Depression is a common comorbid condition in substance abuse disorders. In particular, comorbidity between alcoholism and depression occurs with extremely high prevalence in the general population. Early studies investigating this dual diagnosis issue reported alcohol abuse to occur in almost a quarter of patients with affective disorders [1, 2]. Prevalence rises as high as 32 % if other substance abuse disorders are included [2]. These findings made it clear that enormous challenges lie ahead in tracing the individual etiology of substance abuse and depression, let alone their interaction. Clearly, this dilemma was to produce further difficulties in providing adequate and appropriate treatment for sufferers.

Original languageEnglish (US)
Title of host publicationNeural-Immune Interactions in Brain Function and Alcohol Related Disorders
PublisherSpringer US
Pages167-209
Number of pages43
ISBN (Electronic)9781461447290
ISBN (Print)1461447283, 9781461447283
DOIs
StatePublished - Oct 1 2013

ASJC Scopus subject areas

  • General Medicine
  • General Neuroscience

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