@inbook{59bf13354a284da4850269d8898ef998,
title = "Mouse Models to Study Secondary Cancer Prevention",
abstract = "Secondary prevention is a set of procedures involved in discovering early recurrence, local or systemic metastasis before the clinical signs or symptoms. We describe a mouse model with orthotopic pancreatic tumor implantation followed by distal pancreatectomy. The bioluminescence imaging and MRI could be used for screening the resected primary tumor recurrence and secondary cancer development. Different types of surgical procedures, chemotherapy, or immunotherapy can be engaged in reducing the metastasis potential of primary cancers. This model has been proved to be safe and easy to establish, which can mimic the clinical scenario and expand perspectives for studying the effects of tumor resection and adjuvant or neoadjuvant therapy on secondary cancer prevention.",
keywords = "Metastasis, Murine model, Recurrence, Secondary cancer, Tumor resection",
author = "Le Li and Vidhi Chandra and Florencia McAllister and Yu Zhang",
note = "Publisher Copyright: {\textcopyright} 2022, The Author(s).",
year = "2022",
doi = "10.1007/978-1-0716-2014-4_16",
language = "English (US)",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "215--223",
booktitle = "Methods in Molecular Biology",
}